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The two-dimensional migration pattern of the single HLA-DR beta chain expressed in DRw8 haplotypes is not fully predictive of its activity in antigen presentation.

作者信息

Bouillot M, Choppin J, Sterkers G, Freidel C, Gebuhrer L, Betuel H, Levy J P

机构信息

INSERM U152, CNRS UA 628, Hôpital Cochin, Paris, France.

出版信息

Immunogenetics. 1988;28(1):46-9. doi: 10.1007/BF00372528.

DOI:10.1007/BF00372528
PMID:3378836
Abstract
摘要

相似文献

1
The two-dimensional migration pattern of the single HLA-DR beta chain expressed in DRw8 haplotypes is not fully predictive of its activity in antigen presentation.在DRw8单倍型中表达的单一HLA - DRβ链的二维迁移模式并不能完全预测其在抗原呈递中的活性。
Immunogenetics. 1988;28(1):46-9. doi: 10.1007/BF00372528.
2
Two variants of DRw52, DR3, and DQw2 specificities distinguish two different DR3-bearing extended haplotypes.
Hum Immunol. 1988 Feb;21(2):133-42. doi: 10.1016/0198-8859(88)90088-2.
3
DR-restricted T-cell reactivities associated with the Dw19 specificity can be directed against the products of either locus DRB3 (DRw52c) or locus DRB1.与Dw19特异性相关的DR限制型T细胞反应性可针对DRB3（DRw52c）基因座或DRB1基因座的产物。
Hum Immunol. 1990 Aug;28(4):345-53. doi: 10.1016/0198-8859(90)90029-o.
4
Functional polymorphism of the HLA-DR beta III chain.
Hum Immunol. 1988 Jan;21(1):49-61. doi: 10.1016/0198-8859(88)90080-8.
5
Electrophoretic variation between class II molecules expressed on HLA-DRw8 homozygous typing cells reveals multiple distinct haplotypes.在HLA - DRw8纯合分型细胞上表达的II类分子之间的电泳变异揭示了多个不同的单倍型。
Immunogenetics. 1985;21(1):49-60. doi: 10.1007/BF00372241.
6
Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.在没有恒定链的情况下，抗原可呈递给HLA II类限制性麻疹病毒特异性T细胞克隆。
Proc Natl Acad Sci U S A. 1988 Feb;85(4):1209-12. doi: 10.1073/pnas.85.4.1209.
7
A cellular and functional split in the DRw8 haplotype is due to a single amino acid replacement (DR beta ser 57- asp 57).DRw8单倍型中的细胞和功能分裂是由单个氨基酸替换（DRβ 57位丝氨酸替换为天冬氨酸）所致。
Immunogenetics. 1989;29(5):308-16. doi: 10.1007/BF00352840.
8
Immunochemical analysis of a cell transfected with an HLA-DR gene reveals a new alloantigenic specificity within HLA-DRw52.
Eur J Immunol. 1986 Dec;16(12):1603-8. doi: 10.1002/eji.1830161221.
9
A cytotoxic monoclonal antibody (HU-39) that detects DRw8 + DRw12.一种可检测DRw8 + DRw12的细胞毒性单克隆抗体（HU - 39）。
Hum Immunol. 1987 Jun;19(2):117-26. doi: 10.1016/0198-8859(87)90099-1.
10
Highly polymorphic products of both HLA-DR and HLA-DQ genes contribute to the polymorphism of the HLA-DRw13 haplotype.HLA - DR和HLA - DQ基因的高度多态性产物促成了HLA - DRw13单倍型的多态性。
Immunogenetics. 1986;24(3):177-83. doi: 10.1007/BF00364746.

引用本文的文献

1
A cellular and functional split in the DRw8 haplotype is due to a single amino acid replacement (DR beta ser 57- asp 57).DRw8单倍型中的细胞和功能分裂是由单个氨基酸替换（DRβ 57位丝氨酸替换为天冬氨酸）所致。
Immunogenetics. 1989;29(5):308-16. doi: 10.1007/BF00352840.

本文引用的文献

1
Two populations of Ia-like molecules on a human B cell line.人类B细胞系上的两类Ia样分子。
J Immunol. 1980 Jul;125(1):293-9.
2
Analysis of the HLA-DRw8 haplotype: recognition by HTC typing of three distinct antigen complexes in Caucasians, Native Americans, and Orientals.HLA - DRw8单倍型分析：通过混合淋巴细胞培养分型法识别高加索人、美洲原住民和东方人中三种不同的抗原复合物。
Immunogenetics. 1983;17(4):399-410. doi: 10.1007/BF00372458.
3
Functional subdivision of HLA-DRw8 with influenza-specific cloned cell lines.利用流感特异性克隆细胞系对HLA - DRw8进行功能细分。
Immunogenetics. 1985;22(4):407-12. doi: 10.1007/BF00430924.
4
Molecular, serologic, and functional evidence for an apparent HLA-DR triplet.
J Immunol. 1986 Jul 1;137(1):211-6.
5
Biochemistry of HLA-DRw6: evidence for seven distinct haplotypes.
J Immunol. 1986 May 15;136(10):3767-72.
6
Definition of DW8.2 by primary and secondary mixed lymphocyte cultures.
Hum Immunol. 1985 Jan;12(1):9-21. doi: 10.1016/0198-8859(85)90250-2.
7
Electrophoretic variation between class II molecules expressed on HLA-DRw8 homozygous typing cells reveals multiple distinct haplotypes.在HLA - DRw8纯合分型细胞上表达的II类分子之间的电泳变异揭示了多个不同的单倍型。
Immunogenetics. 1985;21(1):49-60. doi: 10.1007/BF00372241.
8
Polymorphisms within the HLA-DR3 haplotypes. I. HLA-DR polymorphisms detected at the protein and DNA levels are reflected by T-cell recognition.HLA - DR3单倍型内的多态性。I. 在蛋白质和DNA水平检测到的HLA - DR多态性可通过T细胞识别反映出来。
Immunogenetics. 1986;23(6):401-5. doi: 10.1007/BF00372674.
9
HLA-DR beta genes vary in number between different DR specificities, whereas the number of DQ beta genes is constant.
J Immunol. 1985 Sep;135(3):2149-55.
10
HLA-D region antigen-associated invariant polypeptides as revealed by two-dimensional gel analysis. Glycosylation and structural inter-relationships.二维凝胶分析揭示的HLA-D区域抗原相关不变多肽。糖基化和结构相互关系。
J Biol Chem. 1985 Feb 10;260(3):1927-36.