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需要家庭长期氧疗的患者的体重和血清白蛋白水平变化

Changes in Body Weight and Serum Albumin Levels in Patients Requiring Home Long-term Oxygen Therapy.

作者信息

Kayauchi Naomi, Ojima Eiji, Kagohashi Katsunori, Satoh Hiroaki

机构信息

University of Tsukuba, Mito Medical Center, Ibaraki, Japan.

出版信息

Asian Pac Isl Nurs J. 2021;5(4):199-206. doi: 10.31372/20200504.1113.

DOI:10.31372/20200504.1113
PMID:33791407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7993891/
Abstract

To investigate the long-term changes in body weight and serum albumin levels in patients with respiratory failure, and those with chronic heart failure, who were treated with home long-term oxygen therapy (LTOT) to understand the current status and contribute to future measures. Patients with chronic obstructive pulmonary disease (COPD), those with interstitial pneumonia (IP), and those with chronic heart failure (CHF) undergoing home LTOT for 6 months or more between January 2011 and January 2019 were included in the study. Body weight and serum albumin levels were assessed at the start of home LTOT and at the end of the observation period, a minimum of 6 months after commencing home LTOT. Sixty-two patients (29 COPDs, 23 IPs, and 10 CHFs) were included. In COPD patients and IP patients, body weight decreased ( = 0.0017,  = 0.0018, respectively, Wilcoxon signed-rank test). Serum albumin levels decreased in IP patients ( = 0.0185) but not in COPD patients. There was neither significant decrease in body weight nor serum albumin levels in patients with CHF. Chronic respiratory failure patients who have home LTOT were likely to have a decreased nutritional status. In order to provide prolonged home LTOT, medical staff need to pay close attention to the nutritional status of patients receiving home LTOT.

摘要

为了调查接受家庭长期氧疗(LTOT)的呼吸衰竭患者和慢性心力衰竭患者的体重和血清白蛋白水平的长期变化,以了解当前状况并为未来措施提供依据。纳入了2011年1月至2019年1月期间接受家庭LTOT治疗6个月或更长时间的慢性阻塞性肺疾病(COPD)患者、间质性肺炎(IP)患者和慢性心力衰竭(CHF)患者。在家庭LTOT开始时以及观察期结束时(开始家庭LTOT后至少6个月)评估体重和血清白蛋白水平。共纳入62例患者(29例COPD患者、23例IP患者和10例CHF患者)。在COPD患者和IP患者中,体重下降(分别为Wilcoxon符号秩检验,P = 0.0017,P = 0.0018)。IP患者的血清白蛋白水平下降(P = 0.0185),而COPD患者未下降。CHF患者的体重和血清白蛋白水平均无显著下降。接受家庭LTOT的慢性呼吸衰竭患者可能营养状况下降。为了提供长期的家庭LTOT,医务人员需要密切关注接受家庭LTOT患者的营养状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13aa/7993891/e3f9060810a0/apinj-05-199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13aa/7993891/60613d9214de/apinj-05-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13aa/7993891/e3f9060810a0/apinj-05-199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13aa/7993891/60613d9214de/apinj-05-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13aa/7993891/e3f9060810a0/apinj-05-199-g002.jpg

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