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新冠肺炎患者在急性护理环境下使用补充氧气后出院后的死亡率和再入院率。

Mortality and Readmission Rates Among Patients With COVID-19 After Discharge From Acute Care Setting With Supplemental Oxygen.

机构信息

Los Angeles County + University of Southern California (LAC+USC) Medical Center, Los Angeles.

Department of Emergency Medicine, Keck School of Medicine at University of Southern California, Los Angeles.

出版信息

JAMA Netw Open. 2021 Apr 1;4(4):e213990. doi: 10.1001/jamanetworkopen.2021.3990.

DOI:10.1001/jamanetworkopen.2021.3990
PMID:33792728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8017465/
Abstract

IMPORTANCE

To optimize patient outcomes and preserve critical acute care access during the COVID-19 pandemic, the Los Angeles County Department of Health Services developed the SAFE @ HOME O2 Expected Practice (expected practice), enabling ambulatory oxygen management for COVID-19.

OBJECTIVE

To assess outcomes of patients with COVID-19 pneumonia discharged via the expected practice approach to home or quarantine housing with supplemental home oxygen.

DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included 621 adult patients with COVID-19 pneumonia who were discharged from 2 large urban public hospitals caring primarily for patients receiving Medicaid from March 20 to August 19, 2020. Patients were included in the analysis cohort if they received emergency or inpatient care for COVID-19 and were discharged with home oxygen.

INTERVENTIONS

Patients receiving at least 3 L per minute of oxygen, stable without other indication for inpatient care, were discharged from either emergency or inpatient encounters with home oxygen equipment, educational resources, and nursing telephone follow-up within 12 to 18 hours of discharge. Nurses provided continued telephone follow up as indicated, always with physician back-up.

MAIN OUTCOMES AND MEASURES

All-cause mortality and all-cause 30-day return admission.

RESULTS

A total of 621 patients with COVID-19 pneumonia (404 male [65.1%] and 217 female [34.9%]) were discharged with home oxygen. Median age of these patients was 51 years (interquartile range, 45-61 years), with 149 (24.0%) discharged from the emergency department and 472 (76%) discharged from inpatient encounters. The all-cause mortality rate was 1.3% (95% CI, 0.6%-2.5%) and the 30-day return hospital admission rate was 8.5% (95% CI, 6.2%-10.7%) with a median follow-up time of 26 days (interquartile range, 15-55 days). No deaths occurred in the ambulatory setting.

CONCLUSIONS AND RELEVANCE

In this cohort study, patients with COVID-19 pneumonia discharged on home oxygen had low rates of mortality and return admission within 30 days of discharge. Ambulatory management of COVID-19 with home oxygen has an acceptable safety profile, and the expected practice approach may help optimize outcomes, by ensuring right care in the right place at the right time and preserving access to acute care during the COVID-19 pandemic.

摘要

重要性

为了优化患者的治疗效果并在 COVID-19 大流行期间保护重要的急性护理服务,洛杉矶县卫生署制定了 SAFE@HOME O2 预期实践(预期实践),从而实现了 COVID-19 患者的门诊吸氧管理。

目的

评估通过预期实践方式出院至居家或隔离住所、并接受补充家用氧气的 COVID-19 肺炎患者的结局。

设计、地点和参与者:这项回顾性队列研究纳入了 621 名患有 COVID-19 肺炎的成年患者,他们于 2020 年 3 月 20 日至 8 月 19 日从两家大型城市公立医院出院,这些医院主要为接受医疗补助的患者提供服务。如果患者因 COVID-19 接受了急诊或住院治疗,且出院时伴有家用氧气,则将其纳入分析队列。

干预措施

至少接受 3 L/分钟氧气、没有其他住院治疗指征且病情稳定的患者,在急诊或住院期间接受治疗后,将在出院后 12 至 18 小时内,携带家用氧气设备、教育资源和护士电话随访出院。护士会根据需要继续进行电话随访,始终有医生提供支持。

主要结局和测量指标

全因死亡率和全因 30 天内再次入院。

结果

共有 621 名患有 COVID-19 肺炎的患者(404 名男性[65.1%]和 217 名女性[34.9%])接受了家用氧气治疗。这些患者的中位年龄为 51 岁(四分位距,45-61 岁),其中 149 名(24.0%)从急诊部门出院,472 名(76%)从住院部门出院。全因死亡率为 1.3%(95%CI,0.6%-2.5%),30 天内再次入院率为 8.5%(95%CI,6.2%-10.7%),中位随访时间为 26 天(四分位距,15-55 天)。在门诊环境中未发生死亡事件。

结论和相关性

在这项队列研究中,接受家用氧气治疗的 COVID-19 肺炎出院患者的死亡率和 30 天内再次入院率较低。使用家用氧气对 COVID-19 进行门诊管理具有可接受的安全性,预期实践方法可以通过确保在正确的时间、在正确的地点提供正确的护理,并在 COVID-19 大流行期间保护急性护理服务的可及性,来帮助优化治疗效果。

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本文引用的文献

1
Clinical features of COVID-19 mortality: development and validation of a clinical prediction model.COVID-19 死亡率的临床特征:临床预测模型的建立与验证。
Lancet Digit Health. 2020 Oct;2(10):e516-e525. doi: 10.1016/S2589-7500(20)30217-X. Epub 2020 Sep 22.
2
Characteristics of Adult Outpatients and Inpatients with COVID-19 - 11 Academic Medical Centers, United States, March-May 2020.2020 年 3 月至 5 月,美国 11 所学术医疗中心的 COVID-19 成年门诊和住院患者特征。
MMWR Morb Mortal Wkly Rep. 2020 Jul 3;69(26):841-846. doi: 10.15585/mmwr.mm6926e3.
3
Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response.
JMIR Nurs. 2024 Nov 19;7:e44580. doi: 10.2196/44580.
4
Hospital Admission Rates and Mortality Among Emergency Department Patients with COVID-19 Discharged with Remote Patient Monitoring with or without HOME - A Value-Based Approach.采用基于价值的方法,对通过远程患者监测出院的新冠肺炎急诊科患者的住院率和死亡率进行研究,该监测分为有或无家庭监测两种情况。
J Okla State Med Assoc. 2023 Sep-Oct;116(5):167-171.
5
2023 Year in Review: Home Oxygen Therapy.2023 年度回顾:家庭氧疗。
Respir Care. 2024 Aug 24;69(9):1182-1188. doi: 10.4187/respcare.12070.
6
Readmissions for Myocardial Infarction Among Survivors of COVID-19 Hospitalization: Nationwide Analysis From Pandemic Year 2020.新冠病毒肺炎住院幸存者中心肌梗死再入院情况:2020年大流行年的全国性分析
JACC Adv. 2023 Jul 27;2(6):100453. doi: 10.1016/j.jacadv.2023.100453. eCollection 2023 Aug.
7
Analysis of Clinical Criteria for Discharge Among Patients Hospitalized for COVID-19: Development and Validation of a Risk Prediction Model.分析 COVID-19 住院患者出院的临床标准:风险预测模型的建立和验证。
J Gen Intern Med. 2024 Nov;39(14):2649-2661. doi: 10.1007/s11606-024-08856-x. Epub 2024 Jun 27.
8
Designing a Virtual Hospital-at-Home Intervention for Patients with Infectious Diseases: A Data-Driven Approach.为传染病患者设计居家虚拟医院干预方案:一种数据驱动的方法。
J Clin Med. 2024 Feb 8;13(4):977. doi: 10.3390/jcm13040977.
9
Digital health for remote home monitoring of patients with COVID-19 requiring oxygen: a cohort study and literature review.用于对需要吸氧的新冠肺炎患者进行远程居家监测的数字健康:一项队列研究及文献综述
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10
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翻译关于新冠病毒的科学内容以改善临床护理并支持公共卫生应对措施。
JAMA. 2020 Jun 23;323(24):2464-2465. doi: 10.1001/jama.2020.9252.
4
The COVID-19 Pandemic in the US: A Clinical Update.美国的新冠疫情:临床最新情况
JAMA. 2020 May 12;323(18):1767-1768. doi: 10.1001/jama.2020.5788.
5
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JAMA. 2020 Apr 14;323(14):1339-1340. doi: 10.1001/jama.2020.3072.
6
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JAMA. 2020 Mar 17;323(11):1039-1040. doi: 10.1001/jama.2020.1490.
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Development and Implementation of Expected Practices to Reduce Inappropriate Variations in Clinical Practice.减少临床实践中不适当差异的预期实践的制定与实施。
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