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睾丸精原细胞瘤伴派杰样扩散至输精管:一种罕见的组织病理学表现。

Testicular seminoma with pagetoid spread into the vas deferens: A rare histopathological presentation.

作者信息

Ambrosini Francesca, Di Stasio Andrea, Borra Tiziana, Cavallone Barbara, Terrone Carlo, Serao Armando

机构信息

Department of Urology, Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.

Department of Urology, Policlinico San Martino Hospital, University of Genoa, Genoa, Italy.

出版信息

Andrologia. 2021 Jul;53(6):e14061. doi: 10.1111/and.14061. Epub 2021 Apr 1.

DOI:10.1111/and.14061
PMID:33792962
Abstract

Testicular cancer, in particular testicular germ cell tumours, is the most common malignancy in young adult men. Defining prognosis and the best therapeutic strategy is challenging since accurate staging could be controversial. We report an unusual case of seminoma with pagetoid spread into the rete testis and, unexpectedly, also within the epithelium of the vas deferens, up to the margin of excision of the spermatic cord. Focussing on the extremely rare pathological finding and the challenge in defining the stage and the best post-surgical management, we would like to raise some issues about the knowledge gap on this topic.

摘要

睾丸癌,尤其是睾丸生殖细胞肿瘤,是年轻成年男性中最常见的恶性肿瘤。由于准确分期可能存在争议,因此确定预后和最佳治疗策略具有挑战性。我们报告了一例罕见的精原细胞瘤病例,其呈派杰样扩散至睾丸网,出乎意料的是,还扩散至输精管上皮,直至精索切除边缘。鉴于这一极其罕见的病理发现以及确定分期和最佳术后管理方面的挑战,我们想就该主题的知识空白提出一些问题。

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Testicular seminoma with pagetoid spread into the vas deferens: A rare histopathological presentation.睾丸精原细胞瘤伴派杰样扩散至输精管:一种罕见的组织病理学表现。
Andrologia. 2021 Jul;53(6):e14061. doi: 10.1111/and.14061. Epub 2021 Apr 1.
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