Alfawaz Mohammed, Alkhiari Resheed, Albuhayjani Abdulaziz Abdulrahman, Albarrak Abdulmajeed, Alharbi Muath Yousef, Aldubaiyan Adi Abdulaziz R, Alkharraz Abdullah Hamad, Alolayan Omar Abdulaziz, Alrasheedi Omar, Almutairi Nawaf, Aljehani Faisal, Alsolami Enad, Alghamdi Waleed, Jawa Hani
Department of Internal Medicine, College of Medicine, University of Jeddah, Jeddah, Saudi Arabia.
Department of Medicine, College of Medicine, Qassim University, Qassim, Saudi Arabia.
J Family Med Prim Care. 2024 Mar;13(3):827-832. doi: 10.4103/jfmpc.jfmpc_895_23. Epub 2024 Apr 4.
It is well known that celiac disease has a negative influence on patients' health and quality of life. It has a wide range of presentation from symptomless to multiple organ dysfunction but mainly gastrointestinal symptoms. Consequently, it is considered a main cause of mortality, morbidity, and health burden. We aim to evaluate the quality of life affected in gluten-free diet and to identify the serological characteristics of celiac disease patients in the Qassim Region of Saudi Arabia and King Fahad Specialist Hospital.
This is a cross-sectional-based study conducted in King Fahad Specialist Hospital, Saudi Arabia, composed of 58 patients with celiac disease for 9 years between August 2011 and August 2020.
Fifty-eight patents were included (79.3% females and 65.5% married), who were divided according to their ages into five groups. Abdominal pain, diarrhea, and/or weight loss were the major patient complaints. A total of 64% of the patients had a +ve (tTG) IgA test at the time of diagnosis, while 17% were -ve. Of the studied patients, 78% reported that they had undergone a duodenal biopsy sampling. No other significant abnormalities were detected between females and males or among the five diagnosed age groups.
Patients with celiac disease reported poor health-related quality of life across the board. However, social interaction, emotional role functioning, and emotional well-being were the most important factors.
众所周知，乳糜泻会对患者的健康和生活质量产生负面影响。其表现形式广泛，从无症状到多器官功能障碍，但主要为胃肠道症状。因此，它被认为是导致死亡、发病和健康负担的主要原因。我们旨在评估无麸质饮食对生活质量的影响，并确定沙特阿拉伯卡西姆地区和法赫德国王专科医院乳糜泻患者的血清学特征。
这是一项在沙特阿拉伯法赫德国王专科医院进行的横断面研究，研究对象为2011年8月至2020年8月期间的58例乳糜泻患者，研究时间长达9年。
纳入58例患者（79.3%为女性，65.5%已婚），根据年龄分为五组。腹痛、腹泻和/或体重减轻是患者的主要主诉。共有64%的患者在诊断时组织转谷氨酰胺酶（tTG）IgA检测呈阳性，而17%呈阴性。在研究的患者中，78%报告他们接受了十二指肠活检取样。在女性和男性之间或五个诊断年龄组中未检测到其他显著异常。
乳糜泻患者普遍报告健康相关生活质量较差。然而，社交互动、情感角色功能和情感幸福感是最重要的因素。
