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印度儿童和青少年高血压患病率的系统评价和荟萃分析。

Prevalence of Hypertension among Children and Adolescents in India: A Systematic Review and Meta-Analysis.

机构信息

ICMR Advanced Center for Evidence-Based Child Health, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.

出版信息

Indian J Pediatr. 2021 Nov;88(11):1107-1114. doi: 10.1007/s12098-021-03686-9. Epub 2021 Apr 2.

Abstract

OBJECTIVE

To conduct a systematic review to provide pooled estimates of the prevalence of hypertension among children aged less than 18 y in India.

METHODS

Three electronic databases (PubMed, EMBASE, and Web of Science) were searched from inception to August 2020 by using terms related to hypertension, children, prevalence, and India. Studies reporting the prevalence of hypertension, defined based on at least three measurements, were included. Two investigators independently performed the literature search, study selection, and data extraction for this review. Random effect meta-analysis was used to provide pooled estimates of hypertension.

RESULTS

A total of 64 studies were included in this systematic review. The pooled prevalence was 7% (95% CI: 6%-8%) for hypertension, 4% (95% CI: 3%-4.1%) for sustained hypertension and 10% (95% CI: 8%-13%) for prehypertension. While there was no significant difference in hypertension across five different regions of the country, an upward rising trend was observed after the year 2005. Urban children had a higher prevalence of hypertension as compared to their rural counterparts. Children with obesity had a significantly high prevalence of hypertension (29%) than normal-weight children (7%).

CONCLUSION

In this review, it was observed that considerable proportions (7%) of school going children are hypertensive in India. Prevalence was higher in urban and overweight children. This study highlights that hypertension is a public health problem in India; hence, there is a need to implement public health measures to prevent hypertension.

摘要

目的

系统评价印度 18 岁以下儿童高血压的患病率,提供汇总估计值。

方法

通过使用与高血压、儿童、患病率和印度相关的术语,从 2020 年 8 月开始在三个电子数据库(PubMed、EMBASE 和 Web of Science)中进行检索。纳入报告高血压患病率的研究,高血压的定义是基于至少三次测量。两名研究人员独立进行了文献检索、研究选择和数据提取。采用随机效应荟萃分析提供高血压的汇总估计值。

结果

本系统评价共纳入 64 项研究。高血压的汇总患病率为 7%(95%CI:6%-8%),持续性高血压为 4%(95%CI:3%-4.1%),高血压前期为 10%(95%CI:8%-13%)。虽然全国五个不同地区的高血压患病率没有显著差异,但 2005 年后呈上升趋势。与农村儿童相比,城市儿童的高血压患病率更高。肥胖儿童的高血压患病率明显高于正常体重儿童(29%比 7%)。

结论

在这项研究中,印度发现相当比例(7%)的学龄儿童患有高血压。高血压在城市和超重儿童中更为常见。本研究强调了高血压是印度的一个公共卫生问题;因此,需要实施公共卫生措施来预防高血压。

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