Miyauchi A
2nd Dept. of Surgery, Kagawa Medical School.
Gan No Rinsho. 1988 May;34(6):739-43.
A theory to evaluate the benefit of surgery and to predict the prognosis in patients with a malignant tumor by analysis of serum tumor marker levels is proposed, and an analysis of 67 patients with a medullary thyroid carcinoma is reported as an example of its application. This theory incorporates the following concepts: the tumor marker doubling time, the reduction index, the expected prolongation of survival by surgical therapy, and the expected duration of survival after surgery. These parameters allow a quantitative judgement of the surgical therapy and a quantitative prediction of the subsequent prognosis as demonstrated in patients with a medullary thyroid carcinoma.
提出了一种通过分析血清肿瘤标志物水平来评估手术益处并预测恶性肿瘤患者预后的理论，并报告了对67例甲状腺髓样癌患者的分析作为其应用实例。该理论包含以下概念：肿瘤标志物倍增时间、降低指数、手术治疗预期延长的生存期以及术后预期生存期。这些参数能够对手术治疗进行定量判断，并对后续预后进行定量预测，如在甲状腺髓样癌患者中所示。
