Second Degree Bachelor of Science in Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.
Department of Pediatrics, Taipei City Hospital Ren-Ai Branch/Department of Allergy and Immunology, West Garden Hospital, Taipei, Taiwan, ROC.
PLoS One. 2021 Apr 2;16(4):e0249572. doi: 10.1371/journal.pone.0249572. eCollection 2021.
The incidence of allergic rhinitis (AR) has increased rapidly in Taiwan during the past 30 years; however, potential risk factors of AR have yet to be examined. The purpose of this study is to explore the prevalence, personal and environmental risk factors of rhinitis. A cross-sectional survey was conducted in 26418 first graders (6-8 years old) in Taipei with a response rate of 94.6% (24999/26418). Modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires were completed by their parents or main caregivers. Logistic regression was used to examine possible personal and environmental (in early life and current) factors related to rhinitis. The prevalence of rhinitis in the past 12 months was 42.8% in 6-8 years old children. Multivariate logistic regression analysis for both males and females revealed that male gender, antibiotic use in first year of life, bronchiolitis before the age of two years, diagnosed asthma, and diagnosed eczema, having a cat the first year of life were associated with an increased risk of rhinitis. Having older siblings, on the other hand, may reduce the risk of rhinitis. Based on the present study, we may recommend less use of antibiotics the first year of life and not having a cat in the home in the child's first year of life as preventive measures to reduce the risk of rhinitis. From the subgroup analysis, we can take preventive measures for the different risk factors of rhinitis and the severity of rhinitis in each subgroup.
在过去的 30 年中，台湾的过敏性鼻炎（AR）发病率迅速上升；然而，AR 的潜在危险因素尚未得到检验。本研究旨在探讨鼻炎的患病率、个人和环境危险因素。在台北对 26418 名一年级学生（6-8 岁）进行了横断面调查，应答率为 94.6%（24999/26418）。由其父母或主要照顾者填写修订后的国际儿童哮喘和过敏研究（ISAAC）问卷。使用逻辑回归分析可能与鼻炎相关的个人和环境（早期和当前）因素。6-8 岁儿童过去 12 个月鼻炎的患病率为 42.8%。对男性和女性进行多变量逻辑回归分析显示，男性、生命第一年使用抗生素、两岁前毛细支气管炎、已诊断哮喘和已诊断湿疹、生命第一年养猫与鼻炎风险增加有关。另一方面，有兄弟姐妹可能会降低患鼻炎的风险。基于本研究，我们可以建议在生命的第一年减少使用抗生素，并且在孩子的第一年不要在家中养猫，作为降低鼻炎风险的预防措施。从小组分析中，我们可以针对每个亚组中鼻炎的不同危险因素和严重程度采取预防措施。
