Department of Psychology, Drexel University, 3141 Chestnut St, Philadelphia, PA, 19104, USA.
Department of Pediatrics, Children's Hospital of Philadelphia, USA.
Appetite. 2021 Aug 1;163:105231. doi: 10.1016/j.appet.2021.105231. Epub 2021 Mar 31.
Weight suppression (WS) has demonstrated associations with numerous indices of eating behavior, psychopathology and eating disorder prognosis. However, because WS has traditionally been measured as a simple subtraction of current weight from highest past weight at adult height, this calculation is problematic for most individuals with disordered eating, who usually reach their highest past weight during adolescence. Here we propose a new method for computing WS to address this shortcoming, termed "developmental weight suppression" (DWS), and provide a web-based tool for ease of calculation.
DWS is calculated as the difference between one's highest premorbid z-BMI (i.e., BMI z-score), and current z-BMI. z-BMIs were calculated using Cole's lambda-mu-sigma (LMS) approach, in accordance with LMS parameters publicly available from the Center for Disease Control (2010). A web-based user interface is available at https://niuxin.shinyapps.io/devws/, making its computation easier and its adoption by researchers simpler.
By using z-BMIs in place of weights, DWS is more sensitive to the developmentally-relevant factors of age, height, and sex. Preliminary findings suggest that DWS is more strongly related to measures of eating pathology and biological reactions to weight loss than traditionally-computed WS, although more research is needed to test this hypothesis.
体重抑制（WS）与许多饮食行为、精神病理学和饮食障碍预后的指标相关联。然而，由于 WS 传统上被测量为成人身高时当前体重与最高既往体重的简单减法，因此对于大多数饮食失调的人来说，这种计算方法存在问题，因为他们通常在青春期达到最高既往体重。在这里，我们提出了一种新的计算 WS 的方法来解决这个问题，称为“发展性体重抑制”（DWS），并提供了一个基于网络的工具，便于计算。
DWS 是通过一个人的最高前驱 z-BMI（即 BMI z 分数）与当前 z-BMI 之间的差值来计算的。z-BMIs 使用 Cole 的 lambda-mu-sigma（LMS）方法计算，符合可从疾病控制中心获得的 LMS 参数（2010 年）。一个基于网络的用户界面可在 https://niuxin.shinyapps.io/devws/ 上获得，这使得其计算更加容易，并且更容易被研究人员采用。
通过使用 z-BMIs 代替体重，DWS 对年龄、身高和性别等与发育相关的因素更加敏感。初步研究结果表明，DWS 与饮食病理学和对体重减轻的生物学反应的测量指标比传统计算的 WS 更为密切相关，尽管需要更多的研究来检验这一假设。
