Witt Ashley A, Berkowitz Staci A, Gillberg Christopher, Lowe Michael R, Råstam Maria, Wentz Elisabet
Department of Psychology.
Gillberg Neuropsychiatry Center, University of Gothenburg.
J Consult Clin Psychol. 2014 Dec;82(6):1207-11. doi: 10.1037/a0037484. Epub 2014 Jul 21.
Research on anorexia nervosa (AN) has emphasized the importance of low absolute body weight, but emerging research suggests the importance of also considering low body weight relative to an individual's highest premorbid weight (weight suppression; WS).
We investigated whether body mass index and WS at lowest weight (BMI-LW and WS-LW) among adolescents with AN predicted BMI at 6-, 10-, or 18-year follow-up, duration of AN, or total eating disorder duration, including time during which criteria were met for bulimia nervosa or eating disorder not otherwise specified.
Forty-seven cases of AN identified through community screening in Sweden were included. Weight and height data were collected from medical records, school nurse charts, and study follow-up assessments.
Higher WS-LW was associated with higher BMI at 6-year and 10-year follow-up, and this effect was strongest among those with the lowest BMI-LW values. BMI-LW and WS-LW were positively associated with BMI at 18-year follow-up, but there was no significant interaction. There was no significant association between WS-LW and AN duration or eating disorder duration, although eating disorder duration was longer among those with higher BMI-LW, controlling for WS-LW.
Absolute and relative weight status interact to predict weight outcomes in AN over the long term. RESULTS suggest that BMI and WS may be more relevant to the prediction of long-term weight outcomes than to the persistence of other eating disorder symptoms.
神经性厌食症(AN)的研究强调了低绝对体重的重要性,但新出现的研究表明,考虑相对于个体病前最高体重的低体重(体重抑制;WS)也很重要。
我们调查了患有AN的青少年在最低体重时的体重指数和WS(BMI-LW和WS-LW)是否能预测6年、10年或18年随访时的BMI、AN的持续时间或总的饮食失调持续时间,包括符合神经性贪食症或未另行规定的饮食失调标准的时间。
纳入了通过瑞典社区筛查确定的47例AN病例。从医疗记录、学校护士记录和研究随访评估中收集体重和身高数据。
较高的WS-LW与6年和10年随访时较高的BMI相关,且这种效应在BMI-LW值最低的人群中最为明显。BMI-LW和WS-LW与18年随访时的BMI呈正相关,但无显著交互作用。WS-LW与AN持续时间或饮食失调持续时间无显著关联,尽管在控制WS-LW的情况下,BMI-LW较高者的饮食失调持续时间更长。
绝对和相对体重状况相互作用,可长期预测AN的体重结局。结果表明,BMI和WS可能与长期体重结局的预测比与其他饮食失调症状的持续存在更相关。