丙酸倍氯米松气雾剂治疗常年性和季节性鼻炎：五年经验回顾
Beclomethasone dipropionate aerosol in treatment of perennial and seasonal rhinitis: a review of five years' experience.
作者信息
Brown H M, Storey G, Jackson F A
出版信息
Br J Clin Pharmacol. 1977;4 Suppl 3(Suppl 3):283S-286S. doi: 10.1111/j.1365-2125.1977.tb04522.x.
Abstract
- Five years' experience in the use of beclomethasone dipropionate aerosol (BDA) in the treatment of 315 patients with upper respiratory tract allergy is reviewed. 2. A total of 223 patients with perennial rhinitis was treated. In 23, where the nasal allergy had recurred after oral corticosteroid therapy for asthma was withdrawn, BDA was effective in 69% of cases. A similar success rate (68%) was recorded in 169 patients suffering from perennial allergic rhinitis alone, but a satisfactory response was observed in only 45% of 31 patients with nasal polypi. 3. In 92 patients with seasonal allergic rhinitis freedom from symptoms was achieved in 80%. 4. A total of approximately 534 patient-years of treatment has been recorded without any evidence of side-effects either clinically or on nasal biopsy.
摘要
- 回顾了使用丙酸倍氯米松气雾剂（BDA）治疗315例上呼吸道过敏患者的五年经验。2. 共治疗了223例常年性鼻炎患者。其中23例在哮喘口服糖皮质激素治疗停药后鼻过敏复发，BDA在69%的病例中有效。169例单纯患有常年性变应性鼻炎的患者记录了相似的成功率（68%），但在31例鼻息肉患者中只有45%观察到满意的反应。3. 92例季节性变应性鼻炎患者中80%实现了症状缓解。4. 总共记录了约534患者年的治疗，临床或鼻活检均无任何副作用证据。
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