Department of Biomedical Engineering, City University of Hong Kong, Hong Kong.
Department of Bionano Technology, Gachon Bionano Research Institute, Gachon University, Seongnam-si, Gyeonggi-do 461-701, Korea.
Int J Mol Sci. 2021 Mar 28;22(7):3499. doi: 10.3390/ijms22073499.
Antibiotic and multi-drug resistant (MDR) poses a significant threat to public health due to its ability to colonize animals (cold and warm-blooded) and contaminate freshwater supplies. Monitoring antibiotic resistant is traditionally costly, involving the application of phenotypic and genotypic tests over several days. However, with the introduction of cheaper semi-automated devices in the last decade, strain detection and identification times have significantly fallen. This, in turn, has led to efficiently regulated food production systems and further reductions in food safety hazards. This review highlights current and emerging technologies used in the detection of antibiotic resistant and MDR a.
抗生素和多药耐药(MDR)对公共卫生构成重大威胁,因为它能够在动物(冷血和温血动物)中定植并污染淡水供应。传统上,监测抗生素耐药性的成本很高,需要进行数天的表型和基因型测试。然而,在过去十年中,随着更便宜的半自动设备的引入,菌株检测和鉴定的时间已经大大缩短。这反过来又导致了食品生产系统的有效监管和进一步降低食品安全危害。本综述重点介绍了用于检测抗生素耐药性和 MDR 的现有和新兴技术。