Olomouc University Social Health Institute, Palacky University, Univerzitni 22, 779 00 Olomouc, Czech Republic.
Department of Gastroenterology and Digestive Endoscopy, University Hospital-St. Michael's Hospital, Satinskeho 1, 811 08 Bratislava, Slovakia.
Int J Environ Res Public Health. 2021 Mar 21;18(6):3237. doi: 10.3390/ijerph18063237.
Stress has been suggested to play a potential role in inflammatory bowel disease (IBD) pathogenesis, but studies focussing on the occurrence of specific life stress events among IBD patients are scarce. Therefore, the aim of the present study was to explore the association between various life stress events and IBD.
Patients with IBD (N = 98, mean age: 38.45, 54.1% men) were compared to a group of healthy controls (N = 405, mean age: 36.45, 58.0% men) originating from a health survey conducted on a representative population sample of Czech adults. The Life Stressor Checklist-Revised (LSC-R) was used to assess the stressors.
IBD patients had higher odds of reporting life stressors overall ( < 0.001), life stressors before the age of 16 ( < 0.004) and a higher score in traumatic stress ( < 0.005) and interpersonal violence ( < 0.001) when compared to the control group. Gender- and diagnosis-related differences are discussed.
Reporting life stressors experienced during childhood or adulthood is strongly associated with IBD. This should be considered in illness management, especially in a severe course of IBD.
压力被认为在炎症性肠病（IBD）发病机制中发挥潜在作用，但专注于 IBD 患者特定生活压力事件发生的研究很少。因此，本研究旨在探讨各种生活压力事件与 IBD 的关系。
将 IBD 患者（N=98，平均年龄：38.45，54.1%为男性）与来自捷克成年人代表性人群健康调查的健康对照组（N=405，平均年龄：36.45，58.0%为男性）进行比较。使用生活压力检查表修订版（LSC-R）评估压力源。
与对照组相比，IBD 患者总体上报告生活压力源的几率更高（<0.001），16 岁前报告生活压力源的几率更高（<0.004），创伤性压力和人际暴力的评分更高（<0.005 和<0.001）。讨论了与性别和诊断相关的差异。
报告在儿童或成年期经历的生活压力源与 IBD 密切相关。在疾病管理中应考虑到这一点，尤其是在 IBD 严重发作时。
