Department of Gastroenterology and Hepatology, University Hospitals Leuven, 3000 Leuven, Belgium.
Nutrients. 2021 Mar 3;13(3):832. doi: 10.3390/nu13030832.
The food we eat is thought to play a role in both the increasing incidence as well as the course of Crohn's disease. What to eat and what to avoid is an increasingly important question for both patients and physicians. Restrictive diets are widely adopted by patients and carry the risk of inducing or worsening malnutrition, without any guarantees on anti-inflammatory potential. Nevertheless, exploration of novel therapies to improve long-term management of the disease is desperately needed and the widespread use of exclusive enteral nutrition in the induction of paediatric Crohn's disease makes us wonder if a similar approach would be beneficial in adult patients. This narrative review discusses the current clinical evidence on whole food diets in achieving symptomatic and inflammatory control in Crohn's disease and identifies knowledge gaps with areas for future research.
我们所吃的食物被认为在克罗恩病的发病率和病程中都起着一定的作用。对于患者和医生来说，吃什么和避免吃什么是一个日益重要的问题。限制饮食被患者广泛采用，但存在导致或加重营养不良的风险，而且不能保证其抗炎潜力。然而，迫切需要探索新的治疗方法来改善疾病的长期管理，而在小儿克罗恩病的诱导期广泛使用肠内营养也让我们不禁思考，这种类似的方法是否对成年患者有益。本综述讨论了全食物饮食在实现克罗恩病症状和炎症控制方面的现有临床证据，并确定了未来研究的知识空白和领域。
