Dunleavy Katie A, Ungaro Ryan C, Manning Laura, Gold Stephanie, Novak Joshua, Colombel Jean-Frederic
Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
The Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Crohns Colitis 360. 2021 Feb 23;3(1):otab009. doi: 10.1093/crocol/otab009. eCollection 2021 Jan.
Micronutrient deficiencies are common in patients with inflammatory bowel disease (IBD). To date, the literature has focused on vitamin D, vitamin B12, and iron deficiencies.
We report a case series of 20 patients with IBD and vitamin C deficiency treated at a single tertiary care center.
Sixteen (80%) patients had symptoms of clinical scurvy, including arthralgia, dry brittle hair, pigmented rash, gingivitis, easy bruising, and/or brittle nails. Eighteen patients underwent a nutritional assessment, 10 (56%) patients reported complete avoidance of fruits and vegetables, and 3 (17%) reported reduced intake of fruits and vegetables.
Vitamin C deficiency should be considered in IBD patients, particularly those with reduced fruit/vegetable intake, as it can lead to significant signs and symptoms.
微量营养素缺乏在炎症性肠病（IBD）患者中很常见。迄今为止，文献主要关注维生素D、维生素B12和铁缺乏。
我们报告了在一家三级医疗中心接受治疗的20例IBD合并维生素C缺乏患者的病例系列。
16例（80%）患者有临床坏血病症状，包括关节痛、头发干枯易断、色素沉着性皮疹、牙龈炎、易瘀伤和/或指甲易脆。18例患者接受了营养评估，10例（56%）患者报告完全不吃水果和蔬菜，3例（17%）报告水果和蔬菜摄入量减少。
IBD患者，尤其是水果/蔬菜摄入量减少的患者，应考虑维生素C缺乏，因为它可导致明显的体征和症状。
