参与中国小麦花叶病毒感染的长链非编码RNA的全基因组鉴定与特征分析

Genome-Wide Identification and Characterization of Long Noncoding RNAs Involved in Chinese Wheat Mosaic Virus Infection of .

作者信息

Zheng Weiran, Hu Haichao, Lu Qisen, Jin Peng, Cai Linna, Hu Cailin, Yang Jian, Dai Liangying, Chen Jianping

机构信息

College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.

State Key Laboratory for Quality and Safety of Agro-Products, Institute of Plant Virology, Ningbo University, Ningbo 315211, China.

出版信息

Biology (Basel). 2021 Mar 17;10(3):232. doi: 10.3390/biology10030232.

Recent studies have shown that a large number of long noncoding RNAs (lncRNAs) can regulate various biological processes in animals and plants. Although lncRNAs have been identified in many plants, they have not been reported in the model plant . Particularly, the role of lncRNAs in plant virus infection remains unknown. In this study, we identified lncRNAs in response to Chinese wheat mosaic virus (CWMV) infection by RNA sequencing. A total of 1175 lncRNAs, including 65 differentially expressed lncRNAs, were identified during CWMV infection. We then analyzed the functions of some of these differentially expressed lncRNAs. Interestingly, one differentially expressed lncRNA, XLOC_006393, was found to participate in CWMV infection as a precursor to microRNAs in . These results suggest that lncRNAs play an important role in the regulatory network of in response to CWMV infection.

最近的研究表明，大量长链非编码RNA（lncRNA）可调控动植物的各种生物过程。尽管在许多植物中已鉴定出lncRNA，但在模式植物中尚未见报道。特别是，lncRNA在植物病毒感染中的作用仍不清楚。在本研究中，我们通过RNA测序鉴定了响应中国小麦花叶病毒（CWMV）感染的lncRNA。在CWMV感染期间共鉴定出1175个lncRNA，其中包括65个差异表达的lncRNA。然后我们分析了其中一些差异表达lncRNA的功能。有趣的是，发现一个差异表达的lncRNA，即XLOC_006393，作为中的微小RNA前体参与CWMV感染。这些结果表明，lncRNA在响应CWMV感染的调控网络中起重要作用。