Levine S N, Benzel E C, Fowler M R, Shroyer J V, Mirfakhraee M
Department of Internal Medicine, Louisiana State University Medical Center, Shreveport.
Neurosurgery. 1988 May;22(5):937-41.
Lymphocytic adenohypophysitis is a rare nonneoplastic cause of a pituitary mass. We report the case of an 18-year-old woman who presented with complaints of headaches and visual disturbances after an otherwise uncomplicated pregnancy and delivery. She had an elevated serum prolactin level and a pituitary mass visualized by magnetic resonance imaging (MRI). The tissue removed by transsphenoidal resection was an inflammatory mass composed of lymphocytes, plasma cells, and moderate fibrosis surrounding islands of hyperplastic lactotrophs. This is the first case of lymphocytic adenohypophysitis visualized by MRI. As in this case, lymphocytic adenohypophysitis is frequently confused with a prolactin-secreting pituitary tumor before operation and pathological examination of the tissue. The clinical characteristics and radiological features of and an approach to managing patients with lymphocytic adenohypophysitis are reviewed and discussed.
淋巴细胞性垂体炎是导致垂体肿块的一种罕见的非肿瘤性病因。我们报告了一例18岁女性病例，该患者在经历了一次无并发症的妊娠和分娩后，出现头痛和视觉障碍的症状。她的血清催乳素水平升高，磁共振成像（MRI）显示有垂体肿块。经蝶窦切除术切除的组织是一个炎性肿块，由淋巴细胞、浆细胞以及围绕增生性催乳细胞岛的中度纤维化组成。这是首例通过MRI显示的淋巴细胞性垂体炎病例。正如本例所示，淋巴细胞性垂体炎在手术和组织病理检查前常被误诊为分泌催乳素的垂体瘤。本文对淋巴细胞性垂体炎患者的临床特征、影像学特点及治疗方法进行了综述和讨论。
