Tirpák Filip, Greifová Hana, Lukáč Norbert, Stawarz Robert, Massányi Peter
AgroBioTech Research Centre, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, Slovakia.
Department of Animal Physiology, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, Slovakia.
Life (Basel). 2021 Mar 9;11(3):213. doi: 10.3390/life11030213.
Natural processes along with increased industrial production and the irresponsible behavior of mankind have resulted in environmental pollution. Environmental pollutants can be categorized based on their characteristics and appearance into the following groups: physical, biological, and chemical. Every single one of them represents a serious threat to the male reproductive tract despite the different modes of action. Male gonads and gametes are especially vulnerable to the effect of exogenous factors; therefore, they are considered a reliable indicator of environmental pollution. The impact of xenobiotics or radiation leads to an irreversible impairment of fertility displayed by histological changes, modulated androgen production, or compromised spermatozoa (or germ cells) quality. The present article reviews the exogenous threats, male reproductive system, the mode of action, and overall impact on the reproductive health of humans and animals.
自然过程、工业生产的增加以及人类的不负责任行为导致了环境污染。环境污染物可根据其特性和外观分为以下几类：物理污染物、生物污染物和化学污染物。尽管它们的作用方式不同，但每一种都对男性生殖道构成严重威胁。男性性腺和配子对外源因素的影响尤为敏感；因此，它们被视为环境污染的可靠指标。外源生物或辐射的影响会导致生育能力不可逆转的损害，表现为组织学变化、雄激素产生调节异常或精子（或生殖细胞）质量受损。本文综述了外源威胁、男性生殖系统、作用方式以及对人类和动物生殖健康的总体影响。
