• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

阻燃PA6/磷杂菲衍生物纳米复合纺织纤维的抗菌、抗真菌性能、细胞毒性及水生生态毒性新见解

New Insights into Antibacterial and Antifungal Properties, Cytotoxicity and Aquatic Ecotoxicity of Flame Retardant PA6/DOPO-Derivative Nanocomposite Textile Fibers.

作者信息

Vasiljević Jelena, Štular Danaja, Kalčíková Gabriela, Zajc Janja, Šobak Matic, Demšar Andrej, Tomšič Brigita, Simončič Barbara, Čolović Marija, Šelih Vid Simon, Jerman Ivan

机构信息

Faculty of Natural Sciences and Engineering, University of Ljubljana, Aškerčeva 12, 1000 Ljubljana, Slovenia.

National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia.

出版信息

Polymers (Basel). 2021 Mar 15;13(6):905. doi: 10.3390/polym13060905.

DOI:10.3390/polym13060905
PMID:33804277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7998799/
Abstract

The aim of this study was to evaluate the antibacterial and antifungal activity, cytotoxicity, leaching, and ecotoxicity of novel flame retardant polyamide 6 (PA6) textile fibers developed by our research group. The textile fibers were produced by the incorporation of flame-retardant bridged 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) derivative (PHED) in the PA6 matrix during the in situ polymerization process at concentrations equal to 10 and 15 wt% (PA6/10PHED and PA6/15PHED, respectively). Whilst the nanodispersed PHED provided highly efficient flame retardancy, its biological activity led to excellent antibacterial activity against and , as well as excellent antifungal activity against and . The results confirmed leaching of the PHED, but the tested leachates did not cause any measurable toxic effect to the duckweed Lemna minor. The in vitro cytotoxicity of the leached PHED from the PA6/15PHED sample was confirmed for human cells from adipose tissue in direct and prolonged contact. The targeted biological activity of the organophosphinate flame retardant could be beneficial for the development of PA6 textile materials with multifunctional properties and the low ecotoxicity profile, while the PHED's leaching and cytotoxicity limit their application involving the washing processes and direct contact with the skin.

摘要

本研究的目的是评估由我们研究小组开发的新型阻燃聚酰胺6（PA6）纺织纤维的抗菌和抗真菌活性、细胞毒性、浸出性和生态毒性。这些纺织纤维是在原位聚合过程中，通过将阻燃桥连9,10-二氢-9-氧杂-10-磷杂菲-10-氧化物（DOPO）衍生物（PHED）以10 wt%和15 wt%的浓度（分别为PA6/10PHED和PA6/15PHED）掺入PA6基体中制成的。虽然纳米分散的PHED提供了高效的阻燃性，但其生物活性导致对大肠杆菌和金黄色葡萄球菌具有优异的抗菌活性，以及对白色念珠菌和黑曲霉具有优异的抗真菌活性。结果证实了PHED的浸出，但测试的浸出液对浮萍（Lemna minor）没有造成任何可测量的毒性影响。PA6/15PHED样品中浸出的PHED对人脂肪组织细胞的体外细胞毒性在直接和长时间接触时得到了证实。有机次膦酸酯阻燃剂的靶向生物活性可能有利于开发具有多功能特性和低生态毒性的PA6纺织材料，而PHED的浸出性和细胞毒性限制了它们在涉及洗涤过程和与皮肤直接接触的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/acc9ee62b3eb/polymers-13-00905-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/189614f440c9/polymers-13-00905-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/95002624caa3/polymers-13-00905-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/807ea0653cbf/polymers-13-00905-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/1d31ffb5aaf4/polymers-13-00905-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/4637128bf883/polymers-13-00905-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/2e1f797e725c/polymers-13-00905-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/be06e12e0716/polymers-13-00905-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/062ed971e637/polymers-13-00905-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/dd487ad42bc2/polymers-13-00905-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/d653c1157663/polymers-13-00905-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/acc9ee62b3eb/polymers-13-00905-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/189614f440c9/polymers-13-00905-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/95002624caa3/polymers-13-00905-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/807ea0653cbf/polymers-13-00905-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/1d31ffb5aaf4/polymers-13-00905-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/4637128bf883/polymers-13-00905-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/2e1f797e725c/polymers-13-00905-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/be06e12e0716/polymers-13-00905-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/062ed971e637/polymers-13-00905-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/dd487ad42bc2/polymers-13-00905-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/d653c1157663/polymers-13-00905-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2459/7998799/acc9ee62b3eb/polymers-13-00905-g011.jpg

相似文献

1
New Insights into Antibacterial and Antifungal Properties, Cytotoxicity and Aquatic Ecotoxicity of Flame Retardant PA6/DOPO-Derivative Nanocomposite Textile Fibers.阻燃PA6/磷杂菲衍生物纳米复合纺织纤维的抗菌、抗真菌性能、细胞毒性及水生生态毒性新见解
Polymers (Basel). 2021 Mar 15;13(6):905. doi: 10.3390/polym13060905.
2
Effect of Different Flame-Retardant Bridged DOPO Derivatives on Properties of in Situ Produced Fiber-Forming Polyamide 6.不同阻燃桥连二苯基膦氧化物衍生物对原位生成的成纤聚酰胺6性能的影响
Polymers (Basel). 2020 Mar 13;12(3):657. doi: 10.3390/polym12030657.
3
Terminal group effects of DOPO-conjugated flame retardant on polyamide 6: Thermal stability, flame retardancy and mechanical performances.含磷杂环共轭型阻燃剂封端基团对聚酰胺6的影响：热稳定性、阻燃性能及力学性能
Front Chem. 2022 Sep 28;10:1002569. doi: 10.3389/fchem.2022.1002569. eCollection 2022.
4
Effects of Combining Graphene Nanoplatelet and Phosphorous Flame Retardant as Additives on Mechanical Properties and Flame Retardancy of Epoxy Nanocomposite.石墨烯纳米片与磷系阻燃剂复合作为添加剂对环氧纳米复合材料力学性能和阻燃性的影响
Polymers (Basel). 2020 Oct 14;12(10):2349. doi: 10.3390/polym12102349.
5
Characterization of Polyamide 6/Multilayer Graphene Nanoplatelet Composite Textile Filaments Obtained Via In Situ Polymerization and Melt Spinning.通过原位聚合和熔体纺丝制备的聚酰胺6/多层石墨烯纳米片复合纺织长丝的表征
Polymers (Basel). 2020 Aug 10;12(8):1787. doi: 10.3390/polym12081787.
6
Effect of Thermal Conductive Fillers on the Flame Retardancy, Thermal Conductivity, and Thermal Behavior of Flame-Retardant and Thermal Conductive Polyamide 6.导热填料对阻燃导热聚酰胺6的阻燃性、热导率及热行为的影响
Materials (Basel). 2019 Dec 9;12(24):4114. doi: 10.3390/ma12244114.
7
Development of Inherently Flame-Retardant Phosphorylated PLA by Combination of Ring-Opening Polymerization and Reactive Extrusion.通过开环聚合和反应挤出相结合制备固有阻燃性磷酸化聚乳酸
Materials (Basel). 2019 Dec 18;13(1):13. doi: 10.3390/ma13010013.
8
A bio-based phosphaphenanthrene-containing derivative modified epoxy thermosets with good flame retardancy, high mechanical properties and transparency.一种具有良好阻燃性、高机械性能和透明度的生物基含菲磷衍生物改性环氧热固性材料。
RSC Adv. 2021 Sep 17;11(49):30943-30954. doi: 10.1039/d1ra05709j. eCollection 2021 Sep 14.
9
Flame-Retardant Performance of Epoxy Resin Composites with SiO Nanoparticles and Phenethyl-Bridged DOPO Derivative.含SiO纳米粒子和苯乙基桥联DOPO衍生物的环氧树脂复合材料的阻燃性能
ACS Omega. 2020 Dec 24;6(1):666-674. doi: 10.1021/acsomega.0c05208. eCollection 2021 Jan 12.
10
Chain Extension and Synergistic Flame-Retardant Effect of Aromatic Schiff Base Diepoxide on Polyamide 6/Aluminum Diethylphosphinate Composites.芳香族席夫碱二环氧化合物对聚酰胺6/次膦酸铝复合材料的扩链及协同阻燃作用
Materials (Basel). 2019 Jul 10;12(14):2217. doi: 10.3390/ma12142217.

本文引用的文献

1
Synthesis of a novel flame retardant based on DOPO derivatives and its application in waterborne polyurethane.基于二苯基膦氧化物（DOPO）衍生物的新型阻燃剂的合成及其在水性聚氨酯中的应用
RSC Adv. 2019 Mar 11;9(13):7411-7419. doi: 10.1039/c8ra09838g. eCollection 2019 Mar 1.
2
Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics.抗菌和抗病毒功能材料：针对应对类似新冠疫情大流行的化学与生物活性
ACS Pharmacol Transl Sci. 2020 Dec 29;4(1):8-54. doi: 10.1021/acsptsci.0c00174. eCollection 2021 Feb 12.
3
Thermal and Flame Retardant Properties of Phosphate-Functionalized Silica/Epoxy Nanocomposites.
磷酸官能化二氧化硅/环氧树脂纳米复合材料的热性能和阻燃性能
Materials (Basel). 2020 Nov 28;13(23):5418. doi: 10.3390/ma13235418.
4
Assessing the effects of textile leachates in fish using multiple testing methods: From gene expression to behavior.采用多种测试方法评估纺织浸出物对鱼类的影响：从基因表达到行为。
Ecotoxicol Environ Saf. 2021 Jan 1;207:111523. doi: 10.1016/j.ecoenv.2020.111523. Epub 2020 Oct 24.
5
Organophosphorus Flame Retardants: A Global Review of Indoor Contamination and Human Exposure in Europe and Epidemiological Evidence.有机磷阻燃剂：欧洲室内污染和人体暴露的全球评估及流行病学证据。
Int J Environ Res Public Health. 2020 Sep 15;17(18):6713. doi: 10.3390/ijerph17186713.
6
Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?有机磷酸酯阻燃剂：它们是多溴二苯醚令人遗憾的替代品吗？
Environ Sci Technol Lett. 2019 Nov 12;6(11):638-649. doi: 10.1021/acs.estlett.9b00582. Epub 2019 Oct 21.
7
Occurrence of Halogenated Pollutants in Domestic and Occupational Indoor Dust.家用和职业性室内灰尘中卤代污染物的出现。
Int J Environ Res Public Health. 2020 May 27;17(11):3813. doi: 10.3390/ijerph17113813.
8
Effect of Different Flame-Retardant Bridged DOPO Derivatives on Properties of in Situ Produced Fiber-Forming Polyamide 6.不同阻燃桥连二苯基膦氧化物衍生物对原位生成的成纤聚酰胺6性能的影响
Polymers (Basel). 2020 Mar 13;12(3):657. doi: 10.3390/polym12030657.
9
Development of Inherently Flame-Retardant Phosphorylated PLA by Combination of Ring-Opening Polymerization and Reactive Extrusion.通过开环聚合和反应挤出相结合制备固有阻燃性磷酸化聚乳酸
Materials (Basel). 2019 Dec 18;13(1):13. doi: 10.3390/ma13010013.
10
Worker exposure to flame retardants in manufacturing, construction and service industries.工人在制造业、建筑业和服务业中接触阻燃剂。
Environ Int. 2020 Feb;135:105349. doi: 10.1016/j.envint.2019.105349. Epub 2019 Dec 3.