Balasubramaniam Bhuvaneshwari, Ranjan Sudhir, Saraf Mohit, Kar Prasenjit, Singh Surya Pratap, Thakur Vijay Kumar, Singh Anand, Gupta Raju Kumar
Department of Chemical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh 208016, India.
Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh 208016, India.
ACS Pharmacol Transl Sci. 2020 Dec 29;4(1):8-54. doi: 10.1021/acsptsci.0c00174. eCollection 2021 Feb 12.
The ongoing worldwide pandemic due to COVID-19 has created awareness toward ensuring best practices to avoid the spread of microorganisms. In this regard, the research on creating a surface which destroys or inhibits the adherence of microbial/viral entities has gained renewed interest. Although many research reports are available on the antibacterial materials or coatings, there is a relatively small amount of data available on the use of antiviral materials. However, with more research geared toward this area, new information is being added to the literature every day. The combination of antibacterial and antiviral chemical entities represents a potentially path-breaking intervention to mitigate the spread of disease-causing agents. In this review, we have surveyed antibacterial and antiviral materials of various classes such as small-molecule organics, synthetic and biodegradable polymers, silver, TiO, and copper-derived chemicals. The surface protection mechanisms of the materials against the pathogen colonies are discussed in detail, which highlights the key differences that could determine the parameters that would govern the future development of advanced antibacterial and antiviral materials and surfaces.
由新型冠状病毒肺炎(COVID-19)引发的全球大流行,使人们开始意识到要确保采取最佳措施以避免微生物传播。在这方面,关于创造一种能破坏或抑制微生物/病毒实体附着的表面的研究重新引起了人们的兴趣。尽管有许多关于抗菌材料或涂层的研究报告,但关于抗病毒材料使用的数据相对较少。然而,随着更多研究聚焦于这一领域,每天都有新信息被添加到文献中。抗菌和抗病毒化学实体的结合代表了一种潜在的突破性干预措施,可减轻致病因子的传播。在这篇综述中,我们调研了各类抗菌和抗病毒材料,如小分子有机物、合成和可生物降解聚合物、银、二氧化钛以及铜衍生化学品。详细讨论了这些材料针对病原体菌落的表面保护机制,这突出了一些关键差异,这些差异可能决定控制先进抗菌和抗病毒材料及表面未来发展的参数。