从[属名]和[属名]中分离得到的甾体皂苷的结构与生物活性

Thu Zaw Min, Oo Sann Myint, Nwe Thinn Myat, Aung Hnin Thanda, Armijos Chabaco, Hussain Faiq H S, Vidari Giovanni

Department of Chemistry, Kalay University, Kalay 03044, Myanmar.

Department of Chemistry, University of Mandalay, Mandalay 100103, Myanmar.

Molecules. 2021 Mar 29;26(7):1916. doi: 10.3390/molecules26071916.

The species and , that are well-known for different uses in traditional medicines and as indoor ornamental plants with air purifying property, are rich sources of bioactive secondary metabolites. In fact, a wide variety of phytochemical constituents have been isolated so far from about seventeen species. This paper has reviewed the literature of about 180 steroidal saponins, isolated from and species, as a basis for further studies. Saponins are among the most characteristic metabolites isolated from the two genera. They show a great variety in structural motifs and a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-proliferative effects and, in most case, remarkable cytotoxic properties.

该物种以及因在传统医学中有不同用途且作为具有空气净化特性的室内观赏植物而闻名，是生物活性次生代谢产物的丰富来源。事实上，到目前为止，已从约十七个物种中分离出了各种各样的植物化学成分。本文综述了从该物种中分离出的约180种甾体皂苷的文献，作为进一步研究的基础。皂苷是从这两个属中分离出的最具特征性的代谢产物之一。它们在结构基序上表现出极大的多样性，并具有广泛的生物活性，包括抗炎、抗菌、抗增殖作用，而且在大多数情况下具有显著的细胞毒性。