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采用冷壁化学气相沉积工艺在用于医疗应用的钴铬合金（L-605）上获得的石墨烯涂层。

Graphene Coating Obtained in a Cold-Wall CVD Process on the Co-Cr Alloy (L-605) for Medical Applications.

作者信息

Wasyluk Łukasz, Boiko Vitalii, Markowska Marta, Hasiak Mariusz, Saladino Maria Luisa, Hreniak Dariusz, Amati Matteo, Gregoratti Luca, Zeller Patrick, Biały Dariusz, Arkowski Jacek, Wawrzyńska Magdalena

机构信息

Division of Optical Spectroscopy, Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, PL-50-422 Wrocław, Poland.

Carbonmed Spółka z ograniczoną odpowiedzialnością, ul. Okólna 2, PL-50-422 Wrocław, Poland.

出版信息

Int J Mol Sci. 2021 Mar 13;22(6):2917. doi: 10.3390/ijms22062917.

DOI:10.3390/ijms22062917
PMID:33805752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8001714/
Abstract

Graphene coating on the cobalt-chromium alloy was optimized and successfully carried out by a cold-wall chemical vapor deposition (CW-CVD) method. A uniform layer of graphene for a large area of the Co-Cr alloy (discs of 10 mm diameter) was confirmed by Raman mapping coated area and analyzing specific G and 2D bands; in particular, the intensity ratio and the number of layers were calculated. The effect of the CW-CVD process on the microstructure and the morphology of the Co-Cr surface was investigated by scanning X-ray photoelectron microscope (SPEM), atomic force microscopy (AFM), scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS). Nanoindentation and scratch tests were performed to determine mechanical properties of Co-Cr disks. The results of microbiological tests indicate that the studied Co-Cr alloys covered with a graphene layer did not show a pro-coagulant effect. The obtained results confirm the possibility of using the developed coating method in medical applications, in particular in the field of cardiovascular diseases.

摘要

通过冷壁化学气相沉积（CW-CVD）方法对钴铬合金上的石墨烯涂层进行了优化并成功实现。通过对涂覆区域进行拉曼映射并分析特定的G带和2D带，确认了大面积钴铬合金（直径10毫米的圆盘）上均匀的石墨烯层；特别是计算了强度比和层数。通过扫描X射线光电子显微镜（SPEM）、原子力显微镜（AFM）、扫描电子显微镜（SEM）和能量色散X射线光谱（EDS）研究了CW-CVD工艺对钴铬表面微观结构和形貌的影响。进行了纳米压痕和划痕试验以确定钴铬圆盘的力学性能。微生物测试结果表明，覆盖有石墨烯层的研究用钴铬合金未显示促凝作用。所得结果证实了所开发的涂层方法在医疗应用中的可能性，特别是在心血管疾病领域。

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