Farooq Imran, Moriarty Tara J
Faculty of Dentistry, University of Toronto, Toronto, ON M5G 1G6, Canada.
Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1G6, Canada.
Microorganisms. 2021 Mar 23;9(3):663. doi: 10.3390/microorganisms9030663.
Tick-borne infectious diseases can affect many tissues and organs including bone, one of the most multifunctional structures in the human body. There is a scarcity of data regarding the impact of tick-borne pathogens on bone. The aim of this review was to survey existing research literature on this topic. The search was performed using PubMed and Google Scholar search engines. From our search, we were able to find evidence of eight tick-borne diseases (Anaplasmosis, Ehrlichiosis, Babesiosis, Lyme disease, Bourbon virus disease, Colorado tick fever disease, Tick-borne encephalitis, and Crimean-Congo hemorrhagic fever) affecting the bone. Pathological bone effects most commonly associated with tick-borne infections were disruption of bone marrow function and bone loss. Most research to date on the effects of tick-borne pathogen infections on bone has been quite preliminary. Further investigation of this topic is warranted.
蜱传传染病可影响包括骨骼在内的许多组织和器官，骨骼是人体最具多功能性的结构之一。关于蜱传病原体对骨骼影响的数据匮乏。本综述的目的是调查关于该主题的现有研究文献。搜索使用了PubMed和谷歌学术搜索引擎。通过搜索，我们找到了八种蜱传疾病（无形体病、埃立克体病、巴贝斯虫病、莱姆病、波旁病毒病、科罗拉多蜱传热、蜱传脑炎和克里米亚-刚果出血热）影响骨骼的证据。与蜱传感染最常相关的病理性骨骼效应是骨髓功能破坏和骨质流失。迄今为止，关于蜱传病原体感染对骨骼影响的大多数研究都相当初步。有必要对该主题进行进一步调查。
