Fraunhofer Institute of Manufacturing Engineering and Automation IPA, 70569 Stuttgart, Germany.
Institute for Energy Efficiency in Production (EEP), University of Stuttgart, 70569 Stuttgart, Germany.
Biosensors (Basel). 2021 Mar 23;11(3):93. doi: 10.3390/bios11030093.
The technological advantages that biosensors have over conventional technical sensors for odor detection and the role they play in the biological transformation have not yet been comprehensively analyzed. However, this is necessary for assessing their suitability for specific fields of application as well as their improvement and development goals. An overview of biological basics of olfactory systems is given and different odor sensor technologies are described and classified in this paper. Specific market potentials of biosensors for odor detection are identified by applying a tailored methodology that enables the derivation and systematic comparison of both the performance profiles of biosensors as well as the requirement profiles for various application fields. Therefore, the fulfillment of defined requirements is evaluated for biosensors by means of 16 selected technical criteria in order to determine a specific performance profile. Further, a selection of application fields, namely healthcare, food industry, agriculture, cosmetics, safety applications, environmental monitoring for odor detection sensors is derived to compare the importance of the criteria for each of the fields, leading to market-specific requirement profiles. The analysis reveals that the requirement criteria considered to be the most important ones across all application fields are high specificity, high selectivity, high repeat accuracy, high resolution, high accuracy, and high sensitivity. All these criteria, except for the repeat accuracy, can potentially be better met by biosensors than by technical sensors, according to the results obtained. Therefore, biosensor technology in general has a high application potential for all the areas of application under consideration. Health and safety applications especially are considered to have high potential for biosensors due to their correspondence between requirement and performance profiles. Special attention is paid to new areas of application that require multi-sensing capability. Application scenarios for multi-sensing biosensors are therefore derived. Moreover, the role of biosensors within the biological transformation is discussed.
生物传感器在气味检测方面相对于传统技术传感器具有的技术优势,以及它们在生物转化中所发挥的作用,尚未得到全面分析。然而,这对于评估它们在特定应用领域的适用性,以及改进和发展目标,是必要的。本文概述了嗅觉系统的生物学基础,并描述和分类了不同的气味传感器技术。通过应用一种定制的方法,确定了用于气味检测的生物传感器的特定市场潜力,该方法能够推导出和系统比较生物传感器的性能概况以及各种应用领域的要求概况。因此,通过 16 个选定的技术标准,评估生物传感器对定义要求的满足程度,以确定特定的性能概况。此外,选择了一些应用领域,即医疗保健、食品工业、农业、化妆品、安全应用、环境监测,以用于气味检测传感器,比较这些领域中标准的重要性,从而得出特定于市场的要求概况。分析表明,在所有应用领域中被认为最重要的要求标准是高特异性、高选择性、高重复精度、高分辨率、高精度和高灵敏度。根据获得的结果,所有这些标准,除了重复精度之外,生物传感器都有可能比技术传感器更好地满足。因此,生物传感器技术一般来说在所有考虑中的应用领域都具有很高的应用潜力。健康和安全应用,特别是由于其要求和性能概况之间的对应关系,被认为具有很高的生物传感器应用潜力。特别关注需要多传感能力的新应用领域。因此,推导出了多传感生物传感器的应用场景。此外,还讨论了生物传感器在生物转化中的作用。