College of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China.
Key Laboratory of Agro-Products Quality and Safety Control in Storage and Transport Process, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Toxins (Basel). 2021 Mar 31;13(4):251. doi: 10.3390/toxins13040251.
Ochratoxin A (OTA) usually contaminates agricultural products such as grapes, oatmeal, coffee and spices. Light was reported as an effective strategy to control spoilage fungi and mycotoxins. This research investigated the effects of light with different wavelengths on the growth and the production of OTA in and . The results showed that the growth of both fungi were extremely inhibited by UV-B. Short-wavelength (blue, violet) significantly inhibited the production of OTA in both fungi, while the inhibitory effect of white was only demonstrated on . These results were supported by the expression profiles of OTA biosynthetic genes of and . To clarify, the decrease in OTA production is induced by inhibition or degradation; therefore, the degradation of OTA under different wavelengths of light was tested. Under UV-B, the degradation rate of 10 μg/mL OTA standard pure-solution samples could reach 96.50% in 15 days, and the degradation effect of blue light was relatively weak. Furthermore, infection experiments of pears showed that the pathogenicity of both fungi was significantly decreased under UV-B radiation. Thus, these results suggested that light could be used as a potential target for strategies in the prevention and control of ochratoxigenic fungi.
赭曲霉毒素 A（OTA）通常污染农产品，如葡萄、燕麦片、咖啡和香料。据报道，光作为一种有效控制腐败真菌和霉菌毒素的策略。本研究调查了不同波长的光对 和 生长和 OTA 产生的影响。结果表明，UV-B 极抑制了两种真菌的生长。短波长（蓝、紫）显著抑制了两种真菌中 OTA 的产生，而白光是仅对 显示出抑制作用。这些结果得到了 和 中 OTA 生物合成基因表达谱的支持。需要澄清的是，OTA 产量的下降是由抑制或降解引起的；因此，测试了不同波长光下 OTA 的降解。在 UV-B 下，10μg/mL OTA 标准纯溶液样品在 15 天内的降解率可达 96.50%，蓝光的降解效果相对较弱。此外，对梨的感染实验表明，两种真菌的致病性在 UV-B 辐射下显著降低。因此，这些结果表明，光可以作为预防和控制产赭曲霉毒素真菌的潜在目标。
