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SARS-CoV-2 在妊娠中的表现——第一波。

SARS-CoV-2 in Pregnancy-The First Wave.

机构信息

Bissaya Barreto Maternity-Obstetrics Service B, Coimbra Hospital and University Center, 3000 Coimbra, Portugal.

出版信息

Medicina (Kaunas). 2021 Mar 5;57(3):241. doi: 10.3390/medicina57030241.

Abstract

COVID-19, a disease caused by SARS-CoV-2, is a public health emergency. Data on the effect of the virus on pregnancy are limited. We carried out a retrospective descriptive study, in order to evaluate the obstetric results on pregnant women in which SARS-CoV-2 was detected through RT-PCR of the nasopharyngeal swab, at admission to the maternity hospital. From 16 March to 31 July 2020, 12 SARS-CoV-2 positive pregnant women have been hospitalized. Eleven were hospitalized for initiation or induction of labor, corresponding to 0.64% of deliveries in the maternity hospital. One pregnant woman was hospitalized for threatened abortion, culminating in a stillbirth at 20 weeks of gestation. Regarding the severity of the disease, nine women were asymptomatic and three had mild illness (two had associated cough and one headache). Three had relevant environmental exposure and a history of contact with infected persons. None had severe or critical illness due to SARS-CoV-2. There were no maternal deaths. The following gestational complications were observed: one stillbirth, one preterm labor, one preterm prelabor rupture of membranes, and one fetal growth restriction. Four deliveries were eutocic, two vacuum-assisted deliveries and five were cesarean sections. The indications for cesarean section were obstetric. SARS-CoV-2 infection was found in a minority of hospitalized pregnant women in this sample. Most are asymptomatic or have mild illness, from gestational complications to highlight stillbirth and preterm birth. There were no cases of vertical transmission by coronavirus.

摘要

新型冠状病毒肺炎(COVID-19)是由严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)引起的一种公共卫生紧急事件。关于该病毒对妊娠影响的数据有限。本研究通过对鼻咽拭子的逆转录聚合酶链反应(RT-PCR)检测,对在妇产科医院入院的 SARS-CoV-2 阳性孕妇的产科结局进行了回顾性描述性研究。2020 年 3 月 16 日至 7 月 31 日期间,共有 12 例 SARS-CoV-2 阳性孕妇住院。11 例孕妇因分娩或引产入院,占妇产科医院分娩总数的 0.64%。1 例孕妇因先兆流产住院,最终妊娠 20 周时发生死胎。就疾病严重程度而言,9 例孕妇无症状,3 例为轻症(其中 2 例伴有咳嗽,1 例头痛)。3 例有相关环境暴露和与感染者接触史。无孕妇因 SARS-CoV-2 发生重症或危重症。无产妇死亡。观察到以下妊娠并发症:1 例死胎,1 例早产,1 例胎膜早破早产,1 例胎儿生长受限。4 例分娩为顺产,2 例真空辅助分娩,5 例剖宫产。剖宫产的指征为产科因素。在本样本中,住院孕妇中发现 SARS-CoV-2 感染的比例较低。大多数孕妇无症状或症状较轻,从妊娠并发症方面突出表现为死胎和早产。无冠状病毒垂直传播的病例。

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SARS-CoV-2 in Pregnancy-The First Wave.SARS-CoV-2 在妊娠中的表现——第一波。
Medicina (Kaunas). 2021 Mar 5;57(3):241. doi: 10.3390/medicina57030241.

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