Apetrii Mugurel, Timofte Daniel, Voroneanu Luminita, Covic Adrian
Department of Nephrology, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Surgical Department I, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Nutrients. 2021 Mar 16;13(3):956. doi: 10.3390/nu13030956.
Chronic kidney disease (CKD) is a global public health burden, needing comprehensive management for preventing and delaying the progression to advanced CKD. The role of nutritional therapy as a strategy to slow CKD progression and uremia has been recommended for more than a century. Although a consistent body of evidence suggest a benefit of protein restriction therapy, patients' adherence and compliance have to be considered when prescribing nutritional therapy in advanced CKD patients. Therefore, these prescriptions need to be individualized since some patients may prefer to enjoy their food without restriction, despite knowing the potential importance of dietary therapy in reducing uremic manifestations, maintaining protein-energy status.
慢性肾脏病（CKD）是一项全球公共卫生负担，需要进行综合管理以预防和延缓其进展至晚期CKD。营养治疗作为减缓CKD进展和尿毒症的一种策略，其作用在一个多世纪以来一直受到推荐。尽管有一系列连贯的证据表明蛋白质限制疗法有益，但在为晚期CKD患者开营养治疗处方时，必须考虑患者的依从性和顺应性。因此，这些处方需要个体化，因为有些患者可能更愿意不受限制地享受食物，尽管他们知道饮食疗法在减轻尿毒症表现、维持蛋白质能量状态方面的潜在重要性。
