Amphibian Research Center, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan.
Center for Conservation Ecology and Genomics, University of Canberra, Canberra, ACT 2601, Australia.
Cells. 2021 Mar 16;10(3):661. doi: 10.3390/cells10030661.
Translocation between sex-chromosomes and autosomes generates multiple sex-chromosome systems. It happens unexpectedly, and therefore, the evolutionary meaning is not clear. The current study shows a multiple sex chromosome system comprising three different chromosome pairs in a Taiwanese brown frog (). The male-specific three translocations created a system of six sex-chromosomes, ♂XYXYXY-♀XXXXXX. It is unique in that the translocations occurred among three out of the six members of potential sex-determining chromosomes, which are known to be involved in sex-chromosome turnover in frogs, and the two out of three include orthologs of the sex-determining genes in mammals, birds and fishes. This rare case suggests sex-specific, nonrandom translocations and thus provides a new viewpoint for the evolutionary meaning of the multiple sex chromosome system.
性染色体与常染色体之间的易位产生了多种性染色体系统。这种情况出乎意料，因此其进化意义尚不清楚。本研究在一只台湾蟾蜍（）中发现了一种由三条不同染色体对组成的多种性染色体系统。♂XYXYXY-♀XXXXXX 的六个性染色体系统是由三个雄性特异性易位产生的，这在已知涉及青蛙性染色体转换的六个潜在性决定染色体成员中是独一无二的，其中三个易位包括哺乳动物、鸟类和鱼类性决定基因的直系同源物。这种罕见的情况表明性染色体特异性、非随机易位，从而为多种性染色体系统的进化意义提供了一个新的视角。
