Janjic Aleksandar, Cayoren Mehmet, Akduman Ibrahim, Yilmaz Tuba, Onemli Emre, Bugdayci Onur, Aribal Mustafa Erkin
Mitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, Turkey.
Electrical and Electronics Engineering Faculty, Istanbul Technical University, Maslak, 34469 Istanbul, Turkey.
Diagnostics (Basel). 2021 Mar 16;11(3):533. doi: 10.3390/diagnostics11030533.
SAFE (Scan and Find Early) is a novel microwave imaging device intended for breast cancer screening and early detection. SAFE is based on the use of harmless electromagnetic waves and can provide relevant initial diagnostic information without resorting to X-rays. Because of SAFE's harmless effect on organic tissue, imaging can be performed repeatedly. In addition, the scanning process itself is not painful since breast compression is not required. Because of the absence of physical compression, SAFE can also detect tumors that are close to the thoracic wall. A total number of 115 patients underwent the SAFE scanning procedure, and the resultant images were compared with available magnetic resonance (MR), ultrasound, and mammography images in order to determine the correct detection rate. A sensitivity of 63% was achieved. Breast size influenced overall sensitivity, as sensitivity was lower in smaller breasts (51%) compared to larger ones (74%). Even though this is only a preliminary study, the results show promising concordance with clinical reports, thus encouraging further SAFE clinical studies.
SAFE（扫描并早期发现）是一种用于乳腺癌筛查和早期检测的新型微波成像设备。SAFE基于无害电磁波的使用，无需借助X射线就能提供相关的初步诊断信息。由于SAFE对有机组织无害，成像可反复进行。此外，由于无需乳房压迫，扫描过程本身不会产生疼痛。由于不存在物理压迫，SAFE还能检测靠近胸壁的肿瘤。共有115名患者接受了SAFE扫描程序，并将所得图像与现有的磁共振（MR）、超声和乳腺X线摄影图像进行比较，以确定正确的检测率。灵敏度达到了63%。乳房大小影响总体灵敏度，较小乳房（51%）的灵敏度低于较大乳房（74%）。尽管这只是一项初步研究，但结果显示与临床报告有良好的一致性，从而鼓励进一步开展SAFE临床研究。
