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阿曼精神科医生治疗抑郁症的处方实践。

Prescribing practices in the treatment of depression among psychiatrists in Oman.

机构信息

From the Department of Psychiatry (Al-Balushi, AlMaqbali), Sohar Hospital, Sohar, Department of Behavioral Medicine (AlSinawi), College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Ministry of Health (Al-Huseini), Oman.

出版信息

Neurosciences (Riyadh). 2021 Apr;26(2):152-157. doi: 10.17712/nsj.2021.2.20200110.

Abstract

OBJECTIVES

To examine the prescribing patterns of antidepressants among a sample of psychiatrists working in Oman and to compare these practices to the current evidence for prescribing specific antidepressant in particular clinical situations.

METHODS

This retrospective cross sectional study. Massachusetts General Hospital Psychopharmacology Questionnaire, a 10-item questionnaire listing factors that might have influenced the choice of antidepressant medication, was sent to 83 psychiatrists working in governmental health sectors in Oman. The study was done from March to July 2019.

RESULTS

A total number of 78 psychiatrists responded to the questionnaire. Of these, 44 of the psychiatrists (56.4%) believed that one type of antidepressant is more efficacious than others, while 74 psychiatrists (94.9%) indicated that selective serotonin reuptake inhibitors (SSRIs) were their first-line treatment preference. Mirtazapine was chosen as the most likely antidepressant to cause weight gain by two-thirds of the participants. For the treatment of anxious depression and depression with melancholic feature, SSRIs were the first choice of treatment for 64.1% and 7% of respondents, respectively. For depression with atypical features, 42.3% indicated that a monoamine oxidase inhibitor would be their first option.

CONCLUSION

There is a discrepancy between the current antidepressant prescribing practices in Oman and empirical antidepressant-prescribing evidence, and this finding is consistent with previous studies.

摘要

目的

研究在阿曼工作的精神科医生中抗抑郁药的处方模式,并将这些实践与特定临床情况下特定抗抑郁药的处方证据进行比较。

方法

这是一项回顾性的横断面研究。我们向在阿曼政府卫生部门工作的 83 名精神科医生发送了 10 项清单,列出了可能影响抗抑郁药物选择的因素的马萨诸塞州综合医院精神药理学问卷。研究于 2019 年 3 月至 7 月进行。

结果

共有 78 名精神科医生对问卷做出了回应。其中,44 名(56.4%)精神科医生认为一种类型的抗抑郁药比其他药物更有效,而 74 名(94.9%)精神科医生表示选择性 5-羟色胺再摄取抑制剂(SSRIs)是他们的一线治疗首选。三分之二的参与者选择米氮平作为最有可能导致体重增加的抗抑郁药。对于焦虑性抑郁症和有忧郁特征的抑郁症的治疗,SSRIs 分别是 64.1%和 7%的受访者的首选治疗方法。对于具有非典型特征的抑郁症,42.3%的受访者表示单胺氧化酶抑制剂将是他们的首选。

结论

阿曼目前的抗抑郁药处方实践与经验性抗抑郁药处方证据之间存在差异,这一发现与先前的研究一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2306/8024139/eb54760550de/Neurosciences-26-2-152-g001.jpg

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