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新型冠状病毒肺炎的严重神经系统并发症

Severe Neurologic Complications of SARS-CoV-2.

作者信息

Sisniega Daniella C, Reynolds Alexandra S

机构信息

Department of Neurology, 1 Gustave L. Levy Place, Box 1136, New York, NY 10029 USA.

Department of Neurosurgery, The Mount Sinai Hospital, 1 Gustave L. Levy Place, Box 1136, New York, NY 10029 USA.

出版信息

Curr Treat Options Neurol. 2021;23(5):14. doi: 10.1007/s11940-021-00669-1. Epub 2021 Mar 31.

DOI:10.1007/s11940-021-00669-1
PMID:33814894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8009931/
Abstract

PURPOSE OF REVIEW

This review presents an overview of the known neurocritical care complications of severe acute respiratory virus 2 (SARS-CoV-2). We present readers with a review of the literature of severe neurologic complications of SARS-CoV-2 and cases from our institution to illustrate these conditions.

RECENT FINDINGS

Neurologic manifestations are being increasingly recognized in the literature. Some patients can have severe neurologic manifestations, though the true prevalence is unknown.

SUMMARY

Severe neurologic complications of COVID-19 include large vessel occlusion ischemic stroke, intracranial hemorrhage, encephalitis, myelitis, Guillain-Barre syndrome, status epilepticus, posterior reversible encephalopathy syndrome, and hypoxic-ischemic encephalopathy. These conditions can manifest in COVID-19 patients even in the absence of risk factors and must be promptly identified as they can have a high mortality if left untreated.

摘要

综述目的

本综述概述了已知的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的神经重症监护并发症。我们向读者介绍了SARS-CoV-2严重神经系统并发症的文献综述以及我们机构的病例,以说明这些情况。

最新发现

神经系统表现越来越多地在文献中得到认可。一些患者可能有严重的神经系统表现,但其真实患病率尚不清楚。

总结

新型冠状病毒肺炎的严重神经系统并发症包括大血管闭塞性缺血性卒中、颅内出血、脑炎、脊髓炎、吉兰-巴雷综合征、癫痫持续状态、后部可逆性脑病综合征和缺氧缺血性脑病。这些情况即使在没有危险因素的新型冠状病毒肺炎患者中也可能出现,如果不及时治疗,死亡率可能很高,因此必须及时识别。

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