Shnoda Mina, Kassar Kinan, Huffman Deanna L, Sanikommu Vijaya, Poornima Indu
Internal Medicine, Allegheny Health Network, Pittsburgh, USA.
Cardiovascular Disease, Allegheny Health Network, Pittsburgh, USA.
Cureus. 2021 Feb 26;13(2):e13574. doi: 10.7759/cureus.13574.
Dual antiplatelet therapy (DAPT), defined as administration of a P2Y12 receptor inhibitor (clopidogrel, prasugrel, or ticagrelor) and aspirin, is recommended after percutaneous coronary intervention. We describe a case of a 50-year-old gentleman with intolerance to the three previously mentioned P2Y12 inhibitors following the placement of a drug-eluting stent to the left anterior descending artery. To our knowledge, based on a thorough review of the literature, this is the second case reporting a similar medical dilemma. We have discussed the multidisciplinary approach implemented to overcome this clinical challenge, which involved the use of clopidogrel with simultaneous administration of a six-day course of oral steroids.
双重抗血小板治疗（DAPT），定义为使用P2Y12受体抑制剂（氯吡格雷、普拉格雷或替格瑞洛）和阿司匹林，在经皮冠状动脉介入治疗后被推荐使用。我们描述了一例50岁男性患者的病例，该患者在左前降支植入药物洗脱支架后对上述三种P2Y12抑制剂不耐受。据我们所知，基于对文献的全面回顾，这是第二例报告类似医疗困境的病例。我们讨论了为克服这一临床挑战而实施的多学科方法，其中包括使用氯吡格雷并同时给予为期六天的口服类固醇疗程。
