疥疮诊治的最新进展
Recent advances in understanding and treating scabies.
作者信息
Welch Emily, Romani Lucia, Whitfeld Margot J
机构信息
St Vincent's Hospital, University of New South Wales, Sydney, Australia.
Kirby Institute, Sydney, Australia.
出版信息
Fac Rev. 2021 Mar 11;10:28. doi: 10.12703/r/10-28. eCollection 2021.
Scabies is an infestation of the skin caused by the mite In 2017, scabies was recognised by the World Health Organisation as a disease of public importance and was consequently added to the list of neglected tropical diseases. An estimated 200 million people currently have scabies worldwide. Scabies is endemic in many developing countries, with the highest prevalence being in hot, humid climates such as the Pacific and Latin American regions. Scabies causes a host immune response which is intensely itchy. Scratching of the lesions can lead to secondary bacterial infections of the skin, such as impetigo, most commonly caused by or . This can have fatal consequences, such as septicaemia, glomerulonephritis, and rheumatic heart disease. Advances over the past 5 years indicate that mass drug administration is an effective strategy to treat scabies. This review will outline advances in the mite biology, epidemiological understanding, diagnosis, and treatment of scabies.
疥疮是由疥螨引起的一种皮肤感染。2017年，疥疮被世界卫生组织认定为具有公共卫生重要性的疾病，因此被列入被忽视热带病名单。据估计，目前全球有2亿人患有疥疮。疥疮在许多发展中国家呈地方性流行，在太平洋和拉丁美洲等炎热潮湿气候地区患病率最高。疥疮会引发强烈瘙痒的宿主免疫反应。搔抓皮损可导致皮肤继发细菌感染，如脓疱病，最常见的致病菌是 或 。这可能会导致败血症、肾小球肾炎和风湿性心脏病等致命后果。过去5年的进展表明，大规模药物给药是治疗疥疮的有效策略。本综述将概述疥疮在螨生物学、流行病学认识、诊断和治疗方面的进展。
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