Reck R, Störkel S, Meyer A
Department of Otolaryngology, University of Mainz, Federal Republic of Germany.
Ann N Y Acad Sci. 1988;523:100-6. doi: 10.1111/j.1749-6632.1988.tb38504.x.
An 8-year follow-up of Ceravital middle ear prostheses showed there was extremely good tolerance in the middle ear space. Incompatibility phenomena were not observed, and inflammatory reactions were neither caused nor supported by the implants. The tympanoplasties were always performed without interposition of cartilage between the tympanic membrane or the tympanic membrane graft and the disk-shaped portion of the implant, and extrusions were never observed. Long-lasting inflammatory processes appeared to destroy implants the same way they destroy ossicles. Transient inflammatory periods (such as episodes of purulent otitis media, which occurred soon after the prostheses were implanted) did not lead to any remarkable changes of the surface of the implant. In healthy middle ears, the hearing results were stable.
对Ceravital中耳假体进行的8年随访显示，中耳腔对其耐受性极佳。未观察到不相容现象，植入物既未引发也未助长炎症反应。鼓膜成形术在鼓膜或鼓膜移植物与植入物盘状部分之间未插入软骨的情况下进行，且从未观察到植入物挤出。长期炎症过程似乎以与破坏听小骨相同的方式破坏植入物。短暂的炎症期（如假体植入后不久发生的化脓性中耳炎发作）并未导致植入物表面出现任何显著变化。在健康的中耳中，听力结果稳定。
