Gattegno B, Sicard F, Alcaidinho D, Arnaud E, Thibault P
Clinique Urologique, Hôpital Tenon, Paris.
Ann Urol (Paris). 1988;22(2):101-2.
During ESWL, bacteria which may be contained in the stone gets disintegrated. This study evaluates the role of prophylactic antibiotherapy in preventing such complications. Fifty patients whose urine culture was negative were randomized into two groups: the first group (25 patients) received a placebo, the second group received Ceftriaxone 1 g I.V. as a single injection performed 1 hour previous ESWL. There was no positive blood culture and no positive urine culture in the placebo group arm as well as in the antibiotic group. In this study, the risk of infection induced by ESWL seems to be minimal, so that prophylactic antibiotherapy does not appear to be necessary when urine before ESWL is sterile.
在体外冲击波碎石术（ESWL）过程中，结石中可能含有的细菌会被分解。本研究评估预防性抗生素治疗在预防此类并发症中的作用。50例尿培养阴性的患者被随机分为两组：第一组（25例患者）接受安慰剂，第二组在ESWL前1小时静脉注射1g头孢曲松作为单次注射。安慰剂组和抗生素组均未出现血培养阳性和尿培养阳性情况。在本研究中，ESWL诱发感染的风险似乎极小，因此当ESWL前尿液无菌时，预防性抗生素治疗似乎没有必要。
