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泌尿外科诊断和手术操作中的感染预防——一项叙述性综述与建议

Infection Prophylaxis in Urological Diagnostic and Surgical Procedures - A narrative review and recommendations.

作者信息

Truzzi José Carlos, Figueiredo André Avarese, Correia João Antônio Pereira, Pontes José, Cabrini Marcelo, Ramacciotti Lorenzo S, de Campos Caio Cesar Citatini, Anzolch Karin Marise Jaeger, Cunha Antônio Peixoto de Lucena, Mestrinho Bruno V, Koifman Leandro, Broglio Marcos, Barroso Ubirajara, Favorito Luciano A, de Bessa José

机构信息

Escola Paulista de Medicina, Universidade Federal de São Paulo - Unifesp, São Paulo, SP, Brasil.

Faculdade de Medicina, Universidade Federal de Juiz de Fora - UFJF, Juiz de Fora, MG, Brasil.

出版信息

Int Braz J Urol. 2025 Nov-Dec;51(6). doi: 10.1590/S1677-5538.IBJU.2025.0333.

DOI:10.1590/S1677-5538.IBJU.2025.0333
PMID:40705965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12588627/
Abstract

OBJECTIVES

In this review we will provide recommendations for surgical site infection (SSI) prophylaxis in urological diagnostic and surgical procedures.

MATERIAL AND METHODS

We performed a narrative review of the literature in PubMed (Medline), EMBASE, LILACS, Web of Science, and Cochrane Collaboration databases using the terms "infection," "surgery," "urology," and "antibiotic prophylaxis" Results: We suggest recommendations of prophylactic antibiotic in the follow procedures: prostate biopsy, Urethrocystoscopy, Extracorporeal Shock Wave Lithotripsy (ESWL) for Urinary Stones, endoscopic ureterolithotripsy, percutaneous nephrolitothomy, Transurethral Resection of the Prostate (TURP) and Prostatic Enucleation, Transurethral Resection of Bladder Tumor (TURBT), Intravesical Botulinum Toxin Injection, surgical correction of female stress incontinence, Surgical Correction of Pelvic Organ Prolapse, urological prosthesis implantation and Open, Laparoscopic, and Robotic Urologic Surgery Conclusions: Consideration in SSI prophylaxis and the prophylactic antibiotic regimens in several urological procedures are show in this paper and will be useful to urologic practice.

摘要

目的

在本综述中,我们将为泌尿外科诊断和手术操作中的手术部位感染(SSI)预防提供建议。

材料与方法

我们使用“感染”“手术”“泌尿外科”和“抗生素预防”等术语,对PubMed(Medline)、EMBASE、LILACS、科学网和Cochrane协作网数据库中的文献进行了叙述性综述。结果:我们建议在以下手术中使用预防性抗生素:前列腺活检、尿道膀胱镜检查、体外冲击波碎石术(ESWL)治疗尿路结石、内镜输尿管碎石术、经皮肾镜取石术、经尿道前列腺切除术(TURP)和前列腺剜除术、经尿道膀胱肿瘤切除术(TURBT)、膀胱内注射肉毒杆菌毒素、女性压力性尿失禁的手术矫正、盆腔器官脱垂的手术矫正、泌尿外科假体植入以及开放、腹腔镜和机器人辅助泌尿外科手术。结论:本文展示了在几种泌尿外科手术中预防SSI及预防性抗生素方案的考虑因素,对泌尿外科实践将有所帮助。

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本文引用的文献

1
Perioperative Antibiotic Prophylaxis Duration in Patients Undergoing Cystectomy With Urinary Diversion: A Randomized Clinical Trial.接受膀胱切除术和尿流改道术患者的围手术期抗生素预防持续时间:一项随机临床试验。
JAMA Netw Open. 2024 Oct 1;7(10):e2439382. doi: 10.1001/jamanetworkopen.2024.39382.
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Transperineal Is the Way To Go.经会阴入路是首选。
Eur Urol Focus. 2024 Sep;10(5):691-693. doi: 10.1016/j.euf.2024.06.010. Epub 2024 Jul 6.
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Postoperative antibiotic prophylaxis for percutaneous nephrolithotomy and risk of infection: a systematic review and meta-analysis.
经皮肾镜取石术后抗生素预防与感染风险:系统评价和荟萃分析。
Int Braz J Urol. 2024 Mar-Apr;50(2):152-163. doi: 10.1590/S1677-5538.IBJU.2023.0626.
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Transperineal Versus Transrectal Magnetic Resonance Imaging-targeted and Systematic Prostate Biopsy to Prevent Infectious Complications: The PREVENT Randomized Trial.经会阴与经直肠磁共振成像靶向与系统前列腺穿刺活检预防感染性并发症:PREVENT 随机试验。
Eur Urol. 2024 Jul;86(1):61-68. doi: 10.1016/j.eururo.2023.12.015. Epub 2024 Jan 11.
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Comparative Effectiveness Randomized Clinical Trial Using Next-generation Microbial Sequencing to Direct Prophylactic Antibiotic Choice Before Urologic Stone Lithotripsy Using an Interprofessional Model.使用下一代微生物测序通过跨专业模型指导泌尿外科结石碎石术前预防性抗生素选择的比较有效性随机临床试验
Eur Urol Open Sci. 2023 Sep 28;57:74-83. doi: 10.1016/j.euros.2023.09.008. eCollection 2023 Nov.
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Can Perioperative Antibiotic Choice Impact Rates of Infectious Complications After Percutaneous Nephrolithotomy? A Single-Blind, Prospective Randomized Trial.围手术期抗生素选择是否会影响经皮肾镜取石术后感染并发症的发生率?一项单盲、前瞻性随机试验。
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Antibiotic prophylaxis in flexible ureterorenoscopy with negative urine culture.尿液培养阴性的软性输尿管肾镜检查中的抗生素预防
BJUI Compass. 2023 Jul 3;4(6):688-694. doi: 10.1002/bco2.242. eCollection 2023 Nov.
8
Clinical practice guidelines for enhanced recovery after colon and rectal surgery from the American Society of Colon and Rectal Surgeons and the Society of American Gastrointestinal and Endoscopic Surgeons.美国结直肠外科医师学会和美国胃肠内镜外科医师学会发布的结肠和直肠手术后加速康复临床实践指南。
Surg Endosc. 2023 Jan;37(1):5-30. doi: 10.1007/s00464-022-09758-x. Epub 2022 Dec 14.
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One week pre-operative oral antibiotics for percutaneous nephrolithotomy reduce risk of infection: a systematic review and meta-analysis.经皮肾镜取石术术前一周口服抗生素可降低感染风险:系统评价和荟萃分析。
Int Braz J Urol. 2023 Mar-Apr;49(2):184-193. doi: 10.1590/S1677-5538.IBJU.2022.0544.
10
AUA-recommended Antibiotic Prophylaxis for Primary Penile Implantation Results in a Higher, Not Lower, Risk for Postoperative Infection: A Multicenter Analysis.美国泌尿外科学会推荐的原发性阴茎植入抗生素预防导致术后感染风险更高而非更低:一项多中心分析。
J Urol. 2023 Feb;209(2):399-409. doi: 10.1097/JU.0000000000003071. Epub 2022 Nov 16.