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[妇科恶性肿瘤中的热疗]

[Hyperthermia in gynecological malignancy].

作者信息

Sekiba K

机构信息

Dept. of Obstetrics and Gynecology, Okayama University.

出版信息

Gan To Kagaku Ryoho. 1988 Apr;15(4 Pt 2-2):1387-92.

PMID:3382207
Abstract

This paper mainly reports our clinical findings so far obtained from thermotherapy performed as part of a multimodality treatment for gynecological malignant tumors. In our thermotherapeutic method, microwaves at 2.45 GHz were applied for superficial tumors and RF waves at 13.56 MHz capable of warming deeper lesions were locally applied, whereas 70-80 MHz radial-type waves were regionally administered when heating of the entire pelvic cavity was required. However, only three of 103 patients were given thermotherapy alone, 47 were given combined chemotherapy, 47 were given radiotherapy and 6 were given both chemotherapy and radiotherapy. The microwave heating was mainly combined with chemotherapy, and when the results obtained from chemotherapy alone were compared with those of thermochemotherapy in the same regimen, the group treated with thermochemotherapy was found to have a more favorable chemotherapeutic effect and prognosis. RF radial-type hyperthermia with radiotherapy was proved to be more effective for reduction of tumor size and histopathological effect than radiotherapy alone.

摘要

本文主要报告了我们目前从热疗中获得的临床结果,热疗是妇科恶性肿瘤多模式治疗的一部分。在我们的热疗方法中,对于浅表肿瘤应用2.45GHz的微波,对于能够加热更深层病变的13.56MHz的射频波进行局部应用,而当需要加热整个盆腔时,则局部应用70 - 80MHz的径向波。然而,103例患者中只有3例仅接受热疗,47例接受联合化疗,47例接受放疗,6例接受化疗和放疗。微波加热主要与化疗联合使用,当将单纯化疗的结果与相同方案的热化疗结果进行比较时,发现接受热化疗的组具有更良好的化疗效果和预后。事实证明,射频径向热疗联合放疗在缩小肿瘤大小和组织病理学效果方面比单纯放疗更有效。

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