Institute for Scientific Research "Dr. Roberto Rivera Damm", Juárez University of Durango State, Durango, Mexico.
Faculty of Nursing, Juárez University of Durango State, Durango, Mexico.
J Int Med Res. 2021 Apr;49(4):3000605211004020. doi: 10.1177/03000605211004020.
To determine the seroprevalence of immunoglobulin (Ig)G and IgM antibodies and its association with the characteristics of the study population from the northern Mexican city of Durango, Mexico.
Through a cross-sectional study design, inhabitants of Durango City, Mexico were surveyed between June 2018 and November 2018. Serum samples from the subjects were analysed for anti- IgG and IgM antibodies using commercially available enzyme-linked immunosorbent assays. Sociodemographic, clinical, behavioural and housing characteristics were recorded. Data were analysed by bivariate and multivariate analyses.
The study enrolled 413 people, of which 124 (30.0%) and 137 (33.2%) were positive for anti- IgG antibodies and anti- IgM antibodies, respectively. Multivariate analysis showed that seropositivity was associated with professional occupation, alcohol consumption, ill clinical status, memory impairment and a history of surgery.
This is the first study to report the seroepidemiology of infection in an urban general population in the north of Mexico. The seroprevalence of infection found was higher than those previously reported in Mexican studies.
在墨西哥北部城市杜兰戈，确定 IgG 和 IgM 抗体的血清流行率及其与研究人群特征的相关性。
通过横断面研究设计，于 2018 年 6 月至 2018 年 11 月对墨西哥杜兰戈市的居民进行了调查。使用市售酶联免疫吸附试验对研究对象的血清样本进行了抗 IgG 和 IgM 抗体分析。记录了社会人口学、临床、行为和住房特征。通过双变量和多变量分析对数据进行了分析。
该研究纳入了 413 人，其中抗 IgG 抗体和抗 IgM 抗体阳性者分别为 124 人（30.0%）和 137 人（33.2%）。多变量分析显示，血清阳性与职业、饮酒、临床不良状况、记忆障碍和手术史有关。
这是首次在墨西哥北部城市普通人群中报告 感染血清流行病学的研究。本研究中发现的感染血清流行率高于以前在墨西哥研究中报告的流行率。
