Department of Chemistry and Biochemistry, University of Belgrade, Faculty of Agriculture, 11080 Belgrade, Serbia.
Department of Science, Institute for Information Technologies Kragujevac, University of Kragujevac, 34000 Kragujevac, Serbia.
Curr Med Chem. 2021;28(23):4592-4615. doi: 10.2174/0929867328666210325100654.
Type 2 diabetes mellitus is a complicated metabolic disorder characterized by hyperglycemia and glucose intolerance. It is considered a new pandemic and its control involves numerous challenges. Although many of the measures are based on improving life habits, diet is also of vital importance due to bioactive compounds present in food. In this regard, several raw materials have been investigated whose bioactivities seem to slow the progression of this disease. Within these matrices, there are algae of importance, such as brown algae, showing to have beneficial effects on glycemic control. These pieces of evidence are increasing every day due to the development of cell or animal models, which lead to the conclusion that bioactive compounds may have direct effects on decreasing hyperglycemia, enhancing insulin secretion and preventing the formation of amyloid plaques.
2 型糖尿病是一种复杂的代谢紊乱，其特征是高血糖和葡萄糖耐量降低。它被认为是一种新的大流行病，其控制涉及到许多挑战。尽管许多措施都是基于改善生活习惯，但由于食物中的生物活性化合物，饮食也非常重要。在这方面，已经研究了几种原材料，它们的生物活性似乎可以减缓这种疾病的进展。在这些基质中，有一些重要的藻类，如褐藻，对血糖控制有有益的影响。由于细胞或动物模型的发展，这些证据每天都在增加，这导致了生物活性化合物可能直接影响降低高血糖、增强胰岛素分泌和防止淀粉样斑块形成的结论。
