Sokoloff L, Varma A A
Department of Pathology, State University of New York, Stony Brook 11794-8691.
Arthritis Rheum. 1988 Jun;31(6):750-6. doi: 10.1002/art.1780310608.
To investigate the association between chondrocalcinosis (CC) and osteoarthritis (OA), 338 joint specimens were examined histologically (55 knees and 84 hips surgically resected because of idiopathic OA, 106 control knees obtained postmortem, and 93 fractured hips). The risk for CC in the OA knees was sixfold that of the age- and sex-adjusted control sections. CC occurred much less frequently in the hip than in the knee; the association with OA was less clear-cut. It was not possible to resolve by statistical analysis which of the two pathological processes was the horse and which was the cart.
为研究软骨钙质沉着症(CC)与骨关节炎(OA)之间的关联,对338个关节标本进行了组织学检查(55个因特发性OA而手术切除的膝关节和84个髋关节,106个死后获得的对照膝关节,以及93个骨折髋关节)。OA膝关节中CC的风险是年龄和性别调整后的对照切片的6倍。CC在髋关节中的发生频率远低于膝关节;与OA的关联不太明确。通过统计分析无法确定这两种病理过程中哪个是因,哪个是果。