多巴酚丁胺负荷试验作为急性心肌梗死后运动试验的替代方法。
The dobutamine stress test as an alternative to exercise testing after acute myocardial infarction.
作者信息
Mannering D, Cripps T, Leech G, Mehta N, Valantine H, Gilmour S, Bennett E D
机构信息
Department of Medicine, St George's Hospital Medical School, London.
出版信息
Br Heart J. 1988 May;59(5):521-6. doi: 10.1136/hrt.59.5.521.
Abstract
Three weeks after myocardial infarction in 50 patients the effect of the infusion of a graded dose of dobutamine was compared with that of symptom limited treadmill exercise testing. The following variables were measured: blood pressure, heart rate, ST segment changes, Doppler aortic blood flow, and cross sectional echocardiographic dimensions. The heart rate and double product increased more during exercise than during dobutamine infusion, while maximum acceleration in the ascending aorta increased more during dobutamine infusion than during exercise. Significant ST depression was recorded in 22 patients during exercise and in 24 during dobutamine infusion; the concordance between the two tests was 88%. In all cases in which ST segment depression occurred in both tests the site of ST depression was the same. Dobutamine stress testing is an alternative to exercise testing in patients after myocardial infarction.
摘要
50例心肌梗死后三周的患者，接受了不同剂量多巴酚丁胺静脉输注，并与症状限制性平板运动试验作对比。测量了以下变量：血压、心率、ST段变化、多普勒主动脉血流以及超声心动图横截面积。运动期间心率和心率收缩压乘积的增加幅度大于多巴酚丁胺输注期间，而多巴酚丁胺输注期间升主动脉的最大加速度增加幅度大于运动期间。运动期间22例患者记录到显著ST段压低，多巴酚丁胺输注期间为24例；两种试验的一致性为88%。在两种试验均出现ST段压低的所有病例中，ST段压低部位相同。多巴酚丁胺负荷试验可作为心肌梗死后患者运动试验的替代方法。
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