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钕钇铝石榴石激光玻璃体溶解术与有症状玻璃体混浊患者的健康相关生活质量

Nd:YAG laser vitreolysis and health-related quality of life in patients with symptomatic vitreous floaters.

作者信息

García Begoña Gacimartin, Orduna Magán Carlos, Alvarez-Peregrina Cristina, Villa-Collar César, Sánchez-Tena Miguel Ángel

机构信息

Clínica Oftalmológica Orduna, Madrid, Spain.

Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Villaviciosa de Odon, Madrid, Spain.

出版信息

Eur J Ophthalmol. 2021 Apr 7:11206721211008036. doi: 10.1177/11206721211008036.

DOI:10.1177/11206721211008036
PMID:33827286
Abstract

BACKGROUND

The treatment of floaters has consisted primarily of monitoring. The therapeutic approach is based on surgical removal or Nd:YAG laser treatment. The objective of this study was the assessment of the quality of life in patients treated with Nd:YAG laser for floaters.

METHODS

Single-center pretest-posttest design in a cohort of subjects treated with Nd-YAG laser with Ultra Q-Reflex technology. Health-related quality of life of the patients was measured before and after the intervention with the Visual Function Questionnaires VFQ-25 and VFQ-39. Anxiety level was measured with the State-Trait Anxiety Inventory. Visual acuity, contrast sensitivity, and safety parameters were also considered.

RESULTS

Thirty-four patients were included in the study. For the VFQ-25 baseline, the median was 73.05, interquartile range (19.25) versus a final median value of 93.76 (8.73) with  < 0.01. The baseline median for the extended version VFQ-39 was 74.60 (19.01) versus the final median of 95.01 (6.50) with  < 0.001. Regarding the anxiety, according to the STAI questionnaire, there were statistically significant differences between the baseline and the final conditions, with a baseline median of 38 (11) versus a final median of 18 (19);  < 0.001. When the analyses differentiated between patients with and without myopia, there were statistically significant differences for VFQ-25 and VFQ-39.

CONCLUSIONS

This study shows an improvement in the health-related quality of life and a significant decrease in anxiety for patients that have undergone Nd: YAG Ultra-Q Reflex laser vitreolysis for floaters vaporization. The effect found is higher in myopic patients.

摘要

背景

飞蚊症的治疗主要是进行监测。治疗方法基于手术切除或钕:钇铝石榴石(Nd:YAG)激光治疗。本研究的目的是评估接受Nd:YAG激光治疗飞蚊症患者的生活质量。

方法

采用单中心前后测设计,对一组接受Nd - YAG激光Ultra Q - Reflex技术治疗的受试者进行研究。在干预前后,使用视觉功能问卷VFQ - 25和VFQ - 39测量患者的健康相关生活质量。使用状态 - 特质焦虑量表测量焦虑水平。还考虑了视力、对比敏感度和安全参数。

结果

34名患者纳入研究。对于VFQ - 25基线,中位数为73.05,四分位间距为19.25,而最终中位数为93.76(8.73),P < 0.01。扩展版VFQ - 39的基线中位数为74.60(19.01),最终中位数为95.01(6.50),P < 0.001。关于焦虑,根据STAI问卷,基线和最终状况之间存在统计学显著差异,基线中位数为38(1),最终中位数为18(19);P < 0.001。当分析区分近视和非近视患者时,VFQ - 25和VFQ - 39存在统计学显著差异。

结论

本研究表明,接受Nd:YAG Ultra - Q Reflex激光玻璃体溶解术治疗飞蚊症汽化的患者,其健康相关生活质量得到改善,焦虑显著降低。在近视患者中发现的效果更高。

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