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马来西亚单一电子烟使用者中尼古丁依赖量表的改良法格斯特龙测试的开发与评估

The Development and Assessment of Modified Fagerstrom Test for Nicotine Dependence Scale among Malaysian Single Electronic Cigarette Users.

作者信息

Rahman Aziz Ur, Mohamed Mohamad Haniki Nik, Jamshed Shazia, Mahmood Syed, Iftikhar Baig Muhammad Ahsan

机构信息

Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia.

International Islamic University of Malaysia (IIUM), Kuantan Campus, Pahang, Malaysia.

出版信息

J Pharm Bioallied Sci. 2020 Nov;12(Suppl 2):S671-S675. doi: 10.4103/jpbs.JPBS_245_19. Epub 2020 Nov 5.

Abstract

BACKGROUND

The Fagerstrom test for nicotine dependence (FTND) is the most widely used scale for assessing nicotine dependence on conventional tobacco cigarettes (TCGs). But the FTND does not evaluate the subject's nicotine dependence to electronic cigarette (EC).

OBJECTIVE

The aim of this study was to develop and assess an equivalent modified FTND scale that measures the nicotine dependency via EC.

MATERIALS AND METHODS

The investigator developed the equivalent modified FTND scale that scores identical to the original scale, that is, 0-10. The developed scale piloted among 15 EC single users, that is, use only EC verified by carbon monoxide (CO) level of <8ppm. The assessment of the scale was done among 69 EC single users and observed for 1 year to determine their nicotine status.

RESULTS

The modified scale revealed an acceptable Cronbach α value of 0.725. Further test-retest reliability of the scale showed a satisfactory Spearman's rank correlation coefficient value of 0.730 ( > 0.05). A 1-year observation showed that of 69 single users, 11 single users completely stopped nicotine intake, 24 remained as EC single users, 15 shifted to dual-use, and 19 relapsed to TCG. Surprisingly, the EC users who completely stopped nicotine intake after 1 year had a low average nicotine dependence value of 3 that was measured by the modified FTND scale at the baseline.

CONCLUSION

The modified FTND scale precisely identifies the physical dependence to nicotine via EC. Therefore, as per this study results the modified FTND scale can be applied in any EC-related studies to assess nicotine dependency via EC.

摘要

背景

法格斯特龙尼古丁依赖测试(FTND)是评估对传统烟草香烟(TCG)尼古丁依赖最广泛使用的量表。但FTND未评估受试者对电子烟(EC)的尼古丁依赖。

目的

本研究旨在开发并评估一种等效的改良FTND量表,用于测量通过电子烟产生的尼古丁依赖性。

材料与方法

研究者开发了等效的改良FTND量表,其得分与原始量表相同,即0 - 10分。在15名仅使用电子烟的用户中进行了该量表的试用,即仅使用经一氧化碳(CO)水平<8ppm验证的电子烟。在69名单一使用电子烟的用户中对该量表进行评估,并观察1年以确定他们的尼古丁状态。

结果

改良后的量表显示出可接受的Cronbach α值为0.725。该量表进一步的重测信度显示出令人满意的斯皮尔曼等级相关系数值为0.730(>0.05)。1年的观察表明,在69名单一用户中,11名完全停止了尼古丁摄入,24名仍为单一使用电子烟的用户,15名转向了双重使用,19名复吸为使用传统烟草香烟。令人惊讶的是,1年后完全停止尼古丁摄入的电子烟用户在基线时通过改良FTND量表测得的平均尼古丁依赖值较低,为3。

结论

改良后的FTND量表能准确识别通过电子烟产生的对尼古丁的身体依赖。因此,根据本研究结果,改良后的FTND量表可应用于任何与电子烟相关的研究,以评估通过电子烟产生的尼古丁依赖性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1fd/8021063/f123bd8e8821/JPBS-12-671-g001.jpg

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