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区块链在疫苗质量控制中的新结构:用于疫苗防伪和可追溯性的双链结构区块链系统。

A Novel Structure of Blockchain Applied in Vaccine Quality Control: Double-Chain Structured Blockchain System for Vaccine Anticounterfeiting and Traceability.

机构信息

College of Cyberspace Security, Hangzhou Dianzi University, Hangzhou 310018, Zhejiang, China.

London School of Hygiene & Tropical Medicine Keppel Street, London WC1E 7HT, UK.

出版信息

J Healthc Eng. 2021 Mar 19;2021:6660102. doi: 10.1155/2021/6660102. eCollection 2021.

Abstract

BACKGROUND

Vaccine, as an irreplaceable means in herd immunization, is widely applied in prevention for communicable diseases. However, adverse impacts were frequently incurred by fake or expired vaccines in China. Given the necessity of vaccine anticounterfeiting, blockchain-based transaction platform could be practiced as a solution in addressing the issue; however, most of the available experiments focused on single-chain structured design with inventible limitations. Accordingly, exploration for the effectiveness and feasibility of mixed-chains structured platform for vaccine anticounterfeiting and tracing is essentially required.

METHODS

Both public chain and private chain were inserted in anticounterfeiting and tracing platform designing process, which were subsequently simulated in Ethereum environment.

RESULTS

By recording different information in public chain and private chain, partial information privacy protection requirements are realized. The transfer identification module realized the function of vaccine quality supervision and solves the problem of EPC label replication. . Compared with the traditional single-structured design, completeness information could be visited by all stakeholders in double-chain structure, including vaccine suppliers, National Medical Products Administration (NMPA), vaccine purchasers, and the vaccinated.

CONCLUSION

Double-chain structured system for vaccine anticounterfeiting and tracing is more effective.

摘要

背景

疫苗作为群体免疫中不可或缺的手段,被广泛应用于传染病的预防。然而,在中国,假冒或过期疫苗经常会造成不良影响。鉴于疫苗防伪的必要性,可以采用基于区块链的交易平台来解决这个问题;然而,大多数现有实验都集中在单链结构设计上,存在明显的局限性。因此,探索防伪和追踪的混合链结构平台的有效性和可行性是非常必要的。

方法

在防伪和追踪平台的设计过程中同时插入了公有链和私有链,并在以太坊环境中进行了模拟。

结果

通过在公有链和私有链中记录不同的信息,实现了部分信息隐私保护的要求。转让识别模块实现了疫苗质量监督的功能,并解决了 EPC 标签复制的问题。与传统的单结构设计相比,双链结构可以让疫苗供应商、国家药品监督管理局(NMPA)、疫苗购买者和接种者等所有利益相关者都能访问完整的信息。

结论

防伪和追踪的双链结构系统更加有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61a4/8004377/ae541f7f0201/JHE2021-6660102.001.jpg

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