Korhonen Marika, Väistö Juuso, Veijalainen Aapo, Leppänen Marja, Ekelund Ulf, Laukkanen Jari A, Brage Soren, Lintu Niina, Haapala Eero A, Lakka Timo A
Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
School of Medicine, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
J Sports Sci. 2021 Sep;39(17):1980-1987. doi: 10.1080/02640414.2021.1912450. Epub 2021 Apr 8.
We investigated the longitudinal associations of physical activity (PA), sedentary time (ST), and cardiorespiratory fitness (CRF) with arterial health among children. In our primary analyses, we investigated 245 children (girls 51.8%) aged 6-9 years participating in the baseline examinations who had data on arterial health at 2-year follow-up. We also utilized a subsample of 90 children who had a complete arterial health data at baseline and 2-year follow-up. ST (≤1.5 METs), light PA (>1.5-4 METs), moderate PA (>4-7 METs), vigorous PA (>7METs), and moderate-to-vigorous PA (MVPA, >4 METs) were assessed by combined movement and heart rate monitoring and CRF by maximal exercise testing on a cycle ergometer at baseline and 2-year follow-up. Stiffness index (SI) as a measure of arterial stiffness and change in reflection index during exercise test (DRI) as a measure of arterial dilation capacity were assessed by pulse contour analysis. Two-year change in vigorous PA was associated with DRI in boys but not in girls (p=0.021 for interaction). In a subsample analyses, 2-year changes in MPA, VPA, and MVPA were inversely associated with 2-year change in SI. In conclusion, promoting PA at higher intensities may confer larger benefits on arterial health than reducing ST and increasing LPA.
我们研究了儿童身体活动（PA）、久坐时间（ST）和心肺适能（CRF）与动脉健康之间的纵向关联。在我们的主要分析中，我们调查了245名6至9岁参与基线检查的儿童（女孩占51.8%），他们在2年随访时有动脉健康数据。我们还使用了一个由90名儿童组成的子样本，这些儿童在基线和2年随访时拥有完整的动脉健康数据。通过运动和心率监测相结合的方式评估ST（≤1.5代谢当量）、轻度PA（>1.5至4代谢当量）、中度PA（>4至7代谢当量）、剧烈PA（>7代谢当量）以及中度至剧烈PA（MVPA，>4代谢当量），并在基线和2年随访时通过在自行车测力计上进行最大运动测试来评估CRF。通过脉搏轮廓分析评估作为动脉僵硬度指标的僵硬度指数（SI）以及作为动脉扩张能力指标的运动测试期间反射指数变化（DRI）。剧烈PA的2年变化与男孩的DRI相关，但与女孩无关（交互作用p=0.021）。在子样本分析中，MPA、VPA和MVPA的2年变化与SI的2年变化呈负相关。总之，与减少ST和增加LPA相比，促进高强度的PA可能对动脉健康有更大益处。
