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利用新型集成 SLO 超宽视野成像扫频源 OCT 设备进行外周 OCT 成像的可行性。

Feasibility of peripheral OCT imaging using a novel integrated SLO ultra-widefield imaging swept-source OCT device.

机构信息

University of Cambridge, Cambridge, UK.

Vitreous Retina Macula Specialists of Toronto, 3280 Bloor St. West. Suite 310, Etobicoke, ON, M8X 2X3, Canada.

出版信息

Int Ophthalmol. 2021 Aug;41(8):2805-2815. doi: 10.1007/s10792-021-01837-7. Epub 2021 Apr 8.

Abstract

PURPOSE

To describe the feasibility of peripheral OCT imaging in retinal diseases using a novel full-field device.

METHODS

A total of 134 consecutive eyes were referred and imaged on the Optos Silverstone swept-source OCT (SS-OCT) (Optos PLC; Dunfermline, UK). Scanning laser ophthalmoscope (SLO) images and the associated SS-OCT images were obtained in the posterior pole, mid-periphery or far periphery based on the nature of the referral and on new areas of interest observed in the optomap images at the time of imaging.

RESULTS

A total of 134 eyes (96 patients) were enrolled in the study. One hundred and twenty-five eyes (91 patients) with 38 retinal pathologies were prospectively assessed and 9 eyes (5 patients) were excluded due to incomplete image acquisition. The average age of the subjects was 54 years (range 21-92 years). Thirty-nine out of 125 eyes (31%) had macular pathologies. Eighty-six out of 125 eyes (69%) had peripheral only pathologies, an area which cannot be visualized by standard OCT devices with a 50 degree field-of-view.

CONCLUSIONS

The ability to capture peripheral pathologies using an integrated SLO-UWF imaging with full-field swept-source provided high-grade anatomical insight that confirmed the medical and surgical management in a majority of cases. Its use in the mid- and far periphery provides a holistic clinical picture, which can potentially aid in the understanding of various retinal pathologies.

摘要

目的

描述使用新型全场设备在外周视网膜疾病中进行 OCT 成像的可行性。

方法

共有 134 只连续眼被转诊并在 Optos Silverstone 扫频源 OCT(SS-OCT)(Optos PLC;邓弗姆林,英国)上进行成像。根据转诊的性质以及在成像时 optomap 图像中观察到的新的感兴趣区域,在眼底、中周或远周获得扫描激光检眼镜(SLO)图像和相关的 SS-OCT 图像。

结果

共有 134 只眼(96 例患者)纳入本研究。125 只眼(91 例患者)共 38 种视网膜病变进行了前瞻性评估,9 只眼(5 例患者)因图像采集不完整而被排除。受试者的平均年龄为 54 岁(范围 21-92 岁)。39 只眼(31%)有黄斑病变。125 只眼中有 86 只眼(69%)只有周边病变,这是标准的 50 度视野 OCT 设备无法观察到的区域。

结论

使用集成 SLO-UWF 成像和全场扫频源捕捉周边病变的能力提供了高等级的解剖学见解,在大多数情况下证实了对这些病变的医学和手术管理。它在中周和远周的应用提供了一个全面的临床图景,这可能有助于理解各种视网膜病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32cb/8289804/387bd656fff7/10792_2021_1837_Fig1_HTML.jpg

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