Gai Q -Z, Li X -L, Li N, Li L, Meng Z, Chen A -F
Department of Imaging, Yantaishan Hospital, Yantai, 264000, China.
Image Center, Dongchangfu People's Hospital, Liaocheng People's Hospital, Liaocheng, 252000, China.
Clin Transl Oncol. 2021 Oct;23(10):2036-2045. doi: 10.1007/s12094-021-02606-9. Epub 2021 Apr 8.
To explore the application value of multi-slice spiral CT (MSCT), magnetic resonance imaging (MRI) combined with gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer.
The subjects of study were 109 gastric cancer patients with T stages admitted to our hospital for diagnosis and treatment from December 2016 to December 2018. All the patients were examined with MSCT, MRI and gastric contrast-enhanced ultrasonography before operation to observe corresponding imaging results. T staging of gastric cancer patients was conducted according to the examination results, which was then compared with postoperative pathological staging. It was performed to analyze the accuracy of the three diagnostic methods and combined diagnosis of gastric cancer T staging.
The sensitivity of MSCT in the diagnosis of T staging of gastric cancer was 60.00%, 67.74%, 72.22%, 76.47%, the specificity was 95.24%, 88.46%, 86.30%, 94.56% and the diagnostic coincidence rate was 87.16%, 82.57%, 81.65%, 91.74%; the sensitivity of MRI in the diagnosis of T staging of gastric cancer was 68.00%, 70.97%, 77.78%, 76.47%, the specificity was 92.86%, 88.46%, 91.78%, 95.65%, and the diagnostic coincidence rate was 87.16%, 83.49%, 87.16%, 92.66%; the sensitivity of gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer was 80.00%, 83.87%, 86.11%, 82.35%, the specificity was 97.62%, 92.31%, 91.78%, 97.83%, and the diagnostic coincidence rate was 93.58%, 89.91%, 89.91%, 95.41%; the sensitivity of combined MSCT, MRI and gastric contrast-enhanced ultrasonography in the diagnosis of T staging of gastric cancer was 88.00%, 93.55%, 97.22%, 94.12%; the specificity was 100%, 97.44%, 95.89%, 98.91%; and the diagnostic coincidence rate was 97.25%, 96.33%, 96.33%, 98.17%, respectively. Statistical analysis revealed that the sensitivity, specificity and diagnostic coincidence rate of combined detection of the three methods were significantly higher than those of single detection (P < 0.05).
Combined use of MSCT, MRI and gastric contrast-enhanced ultrasonography can significantly improve the diagnostic sensitivity, specificity and diagnostic coincidence rate of T staging of gastric cancer. It may provide a certain reference value for guiding the selection of clinical therapeutic approaches and evaluation of curative effect.
探讨多层螺旋CT（MSCT）、磁共振成像（MRI）联合胃增强超声造影在胃癌T分期诊断中的应用价值。
选取2016年12月至2018年12月在我院诊治的109例T分期胃癌患者作为研究对象。所有患者术前均行MSCT、MRI及胃增强超声造影检查，观察相应影像学结果。根据检查结果对胃癌患者进行T分期，并与术后病理分期进行对比。分析三种诊断方法及联合诊断对胃癌T分期的准确性。
MSCT诊断胃癌T分期的敏感度分别为60.00%、67.74%、72.22%、76.47%，特异度分别为95.24%、88.46%、86.30%、94.56%，诊断符合率分别为87.16%、82.57%、81.65%、91.74%；MRI诊断胃癌T分期的敏感度分别为68.00%、70.97%、77.78%、76.47%，特异度分别为92.86%、88.46%、91.78%、95.65%，诊断符合率分别为87.16%、83.49%、87.16%、92.66%；胃增强超声造影诊断胃癌T分期的敏感度分别为80.00%、83.87%、86.11%、82.35%，特异度分别为97.62%、92.31%、91.78%、97.83%，诊断符合率分别为93.58%、89.91%、89.91%、95.41%；MSCT、MRI联合胃增强超声造影诊断胃癌T分期的敏感度分别为88.00%、93.55%、97.22%、94.12%；特异度分别为100%、97.44%、95.89%、98.91%；诊断符合率分别为97.25%、96.33%、96.33%、98.17%。统计学分析显示，三种方法联合检测的敏感度、特异度及诊断符合率均显著高于单项检测（P＜0.05）。
MSCT、MRI联合胃增强超声造影可显著提高胃癌T分期诊断的敏感度、特异度及诊断符合率。可为临床治疗方案的选择及疗效评估提供一定参考价值。
