Department of Dravyaguna, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Ozone Pharmaceutical Ltd., Ozone House, Block A-3, 1 LSC, Janak Puri, New Delhi, India.
J Ethnopharmacol. 2021 Aug 10;276:114101. doi: 10.1016/j.jep.2021.114101. Epub 2021 Apr 5.
Withania somnifera (L.) Dunal (Physalis somnifera L.) is a fairly known perennial shrub of Solanaceae family, and is used in Ayurveda- Traditional Indian Medicine (TIM), since ancient times. It is well known as Ashwagandha in Sanskrit language in Ayurvedic classics. Its Mula (root) is recommended for health and healing, and the number of single and compound formulation is prescribed rationally. It is believed that the species name-somnifera is coined based on popular use to "induce sleep" in Ayurveda.
The present study was aimed to bring out the experience-based traditional uses of Ashwagandha for health and healing with an emphasis on the pharmacological and biochemical scientific evidences to corroborate them. The scientific evidences have been explored from the national and international publications.
A comprehensive literary search of Ayurvedic classics was carried out systematically regarding Ashwagandha for its rationality behind the traditional uses. To excavate the subject matter, the original Ayurvedic scriptures and several standard Ayurvedic texts of different period was studied insightfully for meaningful contribution. It is to be noted that the primary source of knowledge was considered in writing this manuscript without any biased attitude. The available literature on Ashwagandha was also searched to ascertain the basis of scientific Latin name and correct identity. The Ayurvedic Pharmacopoeia and other relevant scientific works were also taken into consideration to make the subject matter more clearly to the scientific world. For the scientific evidence of the uses, the international and national Journals and other published material were also searched to make it inquisitiveness to the scholars interested in Ayurvedic medicinal plants.
The present paper throws ancient luminosity behind the therapeutic uses of one of the promising plant drug i.e., Ashwagandha of ancient India even to the present time. The scientific evidences corroborate the rationality ascribed in available Ayurvedic classics of various period of India has been gained.
The study explores that the first reference of Ashwagandha with its significant nomenclature, useful part, properties, action, and eloquent uses has its footprint in the original texts of Ayurveda. In later works enhanced knowledge with traditional uses continued even today. Several single and compound formulations have been found to maintain the health and to alleviate the disorders rationally. It is worthy to note here that the scientific evidences corroborate the uses practiced in Ayurveda.
南非醉茄(L.)邓纳尔(Physalis somnifera L.)是茄科一种相当知名的多年生灌木,自古以来就在印度阿育吠陀传统医学(TIM)中使用。在阿育吠陀经典中,它的梵语名称为 Ashwagandha。其根(root)被推荐用于健康和治疗,并且合理规定了单一和复合配方的数量。据信,物种名称-somnifera 是根据在阿育吠陀中“诱导睡眠”的流行用途而创造的。
本研究旨在阐明 Ashwagandha 在健康和治疗方面的基于经验的传统用途,并强调药理学和生化科学证据来证实这些用途。科学证据已从国内外出版物中进行了探索。
系统地对阿育吠陀经典中关于 Ashwagandha 的文献进行了全面检索,以了解其传统用途背后的合理性。为了挖掘主题,深入研究了原始的阿育吠陀经文和不同时期的几个标准阿育吠陀文本,以做出有意义的贡献。需要注意的是,在撰写本文时,主要来源的知识被认为是没有任何偏见的。还搜索了关于 Ashwagandha 的现有文献,以确定科学拉丁名称和正确身份的基础。还考虑了阿育吠陀药典和其他相关科学著作,以使主题更清晰地呈现给对阿育吠陀药用植物感兴趣的学者。
本文揭示了古印度有希望的植物药物之一 Ashwagandha 的治疗用途背后的古老光芒,甚至延续到了现在。已获得各个时期印度的阿育吠陀经典中归因于其的合理性的科学证据。
研究表明,Ashwagandha 的第一个参考及其具有重要命名、有用部分、特性、作用和雄辩用途的参考,在阿育吠陀的原始文本中就有其足迹。在后来的作品中,即使在今天,也继续增强了传统用途的知识。已经发现几种单一和复合配方可以合理地保持健康并缓解疾病。值得注意的是,科学证据证实了在阿育吠陀中实践的用途。