Department of Neurology, Duke University School of Medicine, USA.
Duke University Hospital (DUH) Case Management, Duke Health, USA.
Complement Ther Clin Pract. 2021 May;43:101377. doi: 10.1016/j.ctcp.2021.101377. Epub 2021 Mar 31.
Parkinson's Disease (PD) leads to poor quality of life and caregiver burden. Mindfulness-based stress reduction (MBSR) may improve these symptoms. We assessed the impact of a 9-week MBSR course on people with PD (PwP) and their care partners (CPs).
Participants completed questionnaires at screening, at the end of the course, and at 3-month follow-up: Parkinson's Disease Quality-39 (PDQ-39, PD only), Zarit Burden Inventory (ZBI, CP only) and Mindful Attention Awareness Scale (MAAS, both). The primary outcome measure was change in PDQ-39 (for PwP) or ZBI (for CP). Patient-reported scales were analyzed quantitatively; qualitative data on perceived effectiveness was collected.
53.8% PwP and 100% CPs completed the course. Among PwP, there was a significant reduction in MAAS(p < 0.001) and in PDQ-39 (p = 0.008). CPs experienced an increase in MAAS (p = 0.02) but no change in ZBI (p = 0.239). Qualitatively, both PwP and CPs expressed satisfaction with the course.
MBSR improves mindful awareness in CPs and improves health-related quality of life in PwP.
帕金森病（PD）导致生活质量下降和照顾者负担增加。基于正念的减压（MBSR）可能会改善这些症状。我们评估了为期 9 周的 MBSR 课程对帕金森病患者（PwP）及其照顾者（CPs）的影响。
参与者在筛查时、课程结束时和 3 个月随访时完成了问卷：帕金森病生活质量问卷-39 项（PDQ-39，仅针对 PD）、Zarit 负担量表（ZBI，仅针对 CP）和正念注意意识量表（MAAS，两者都有）。主要观察指标是 PDQ-39（针对 PwP）或 ZBI（针对 CP）的变化。对患者报告的量表进行定量分析；收集关于感知效果的定性数据。
53.8%的 PwP 和 100%的 CP 完成了课程。在 PwP 中，MAAS（p<0.001）和 PDQ-39（p=0.008）显著降低。CPs 的 MAAS 增加（p=0.02），但 ZBI 没有变化（p=0.239）。定性研究中，PwP 和 CP 均对课程表示满意。
MBSR 可提高 CP 的正念意识，并改善 PwP 的健康相关生活质量。
