Jiangxi Province Hospital of Integrated Chinese and Western Medicine.
The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Medicine (Baltimore). 2021 Apr 9;100(14):e25281. doi: 10.1097/MD.0000000000025281.
Menstrual irregularities (MI) is 1 of the most common clinical gynaecological diseases, with abnormal menstrual cycles, abnormal bleeding, and abdominal pain before or during menstruation as the main clinical manifestations. In modern medicine, abnormalities in the function of the pituitary gland, hypothalamus, and ovaries can affect menstruation. Currently, hormone levels in the body are mostly regulated by hormonal drugs, but these drugs can lead to hormonal imbalance, which can lead to adverse reactions. Many clinical studies have reported that moxibustion has a good effect on MI treatment, but there is no relevant systematic review. So the purpose of this study is to evaluate the effectiveness and safety of moxibustion in treating MI.
The following 8 electronic databases will be searched, including PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure, Web of Science, Chinese Scientific Journal Database, Wanfang Database, and Chinese Biomedical Literatures Database from their inception to 1 December 2020 without any restrictions. Researchers retrieve the literature and extracted the data, evaluation of research methods, quality of literature. The outcomes will include total effective rate, incidence of any adverse events. We use the Cochrane Risk of a bias assessment tool to evaluate methodological qualities. Data synthesis will be completed by RevMan 5.3.0.
We will show the results of this study in a peer-reviewed journal.
This meta-analysis will provide reliable evidence for treatment of menstrual irregularities.
INPLASY2020120042.
月经不调（MI）是最常见的妇科临床疾病之一，以月经周期异常、异常出血、月经前或月经期间腹痛为主要临床表现。在现代医学中，垂体、下丘脑和卵巢功能异常会影响月经。目前，主要通过激素药物调节体内激素水平，但这些药物会导致激素失衡，引起不良反应。许多临床研究报告艾灸对 MI 治疗有较好的效果，但没有相关的系统评价。因此，本研究旨在评价艾灸治疗 MI 的有效性和安全性。
将检索 PubMed、Embase、Cochrane 图书馆、中国知网、Web of Science、中国科学引文数据库、万方数据库和中国生物医学文献数据库从建库至 2020 年 12 月 1 日，不设任何限制。研究人员检索文献并提取数据，评价研究方法、文献质量。结局指标包括总有效率、任何不良事件的发生率。采用 Cochrane 偏倚风险评估工具评价方法学质量。数据合成将采用 RevMan 5.3.0 完成。
将在同行评议期刊上展示本研究的结果。
本荟萃分析将为月经不调的治疗提供可靠的证据。
INPLASY 注册号：INPLASY2020120042。
